超声结合血清CA125对绝经后卵巢肿瘤的诊断价值

The Differential diagnosis of ultrasonography combined with serum CA125 for patients with postmenopausal benign and malignant ovarian

目的探讨超声结合血清CA125对绝经后卵巢肿瘤的诊断价值,帮助患者更好地接受手术,提高生存率。方法选择浙江丽水市中心医院2009年1月—2014年1月收治的100例绝经后卵巢肿物患者,所有患者均通过血清CA125和阴道B超检查,采用t检验和单向方差对绝经后卵巢肿瘤患者的病理类型、恶性肿瘤与超声形态的关系、血清CA125不同诊断界点对卵巢癌诊断的性能进行分析。结果患者经过超声检查后,其特征与卵巢肿瘤的良恶性有关。21例囊实性卵巢肿物患者中,有8例为恶性肿瘤,在8例实性卵巢肿物中,有4例患者为恶性,而在71例囊性卵巢肿物中,患者全部为良性。对患者的肿物性质、腹水、CA125、绝经年限、侧别、肿瘤最大经线进行分析后,差异有统计学意义(P<0.05)。对患者的血清CA125及卵巢恶性肿瘤的相关性进行分析,其中在90(血清CA125≤35 U/ml)例正常患者中,4例患者检测后为恶性,在10例(血清CA125>35 U/ml)患者中,7例患者检测后为卵巢恶性肿瘤,对比分析后,差异有统计学意义(χ2=31.094,P<0.05)。结论超声联合检测血清CA125能够帮助患者尽早地发现恶性肿瘤患者,及时地进行手术治疗,提高生存率。

Objective To investigate the serum CA125 combined with ultrasound in the diagnosis of ovarian cancer after menopause and judge the surgery whether it is helpful. Methods 100 cases of patients with postmenopausal benign and malignant ovarian from January 2009 to January 2014 were chosen in our hospital to receive treatment. All patients were treated by serum CA125 and vaginal ultrasound B. The histological type of ovarian cancer in postmenopausal, the relation- ship between ultrasound and forms of cancer and serum CA125 different diagnostic boundary point performance against o- varian cancer diagnosis tested with T-test and one-way ANOVA were observed. Results Patients after uhrasonography ,its characteristics were related to benign and malignant ovarian tumors. In 21 cases of cystic ovarian tumor, eight cases were malignant tumors. In 8 cases of patients with solid ovarian tumor, there were four cases of patients with malignant, while in 71 cases of cystic ovarian tumor, all patients were benign, after the analysis, the differences of the nature of tumor, ascites, CA125 ,menopause,the sides of patients and tumor maximum warp were statistically significant between the two groups （P 〈 0.05 ）. Serum CA125 for ovarian cancer patients and relevance of the analysis, including 90 cases of patients with normal serum CA125 values, only five cases of patients with malignant ,while 10 patients with serum CA125 values in ex- cess of 35 U/m1,7 suffering malignant, the difference was statistically significant （ X^2 = 31. 094, P 〈 0.05 ）. Conclusion Ultrasound and CA125 values can help to find cancer patients earlier,treat timely, and improve survival.