186例青年脑卒中患者临床病因及危险因素分析

Analysis of clinical etiology and risk factors of 186 cases young cerebral stroke patients

目的总结温州市中心医院186例青年脑卒中患者病例资料,分析青年脑卒中的临床特点及病因,并探讨青年脑卒中的危险因素。方法回顾性分析2010年1月—2014年6月间该院收治的186例青年脑卒中患者病例,对青年脑卒中的临床特点和病因进行总结分析。并选取同期186名在该院门诊进行健康体检者作为对照组,通过单因素和Logistic分析对青年脑卒中的危险因素进行统计分析。结果 186例青年脑卒中患者包括89例出血性脑卒中和97例缺血性脑卒中,临床发病率最高的疾病主要包括:蛛网膜下腔出血(19.4%)、基底节区出血(17.7%)、脑血栓形成(25.3%)、脑栓塞(14.5%)。青年脑卒中的发病原因主要为高血压(42.5%)、动脉粥样硬化(17.7%)、脑动脉瘤(9.7%)。单因素和Logistic分析结果显示高血压、高血脂、脑卒中家族史、偏头痛、吸烟、饮酒是青年脑卒中的危险因素。结论青年脑卒中临床蛛网膜下腔出血、基底节区出血、脑血栓形成、脑栓塞的发病率最高。青年脑卒中的主要病因包括高血压、动脉粥样硬化、脑动脉瘤。青年脑卒中的主要危险因素包括高血压、高血脂、脑卒中家族史、偏头痛、吸烟、饮酒。

Objective To summary the information of 186 cases of young cerebral stroke, analyze the clinical characteris- tics and etiology of young cerebral stroke, and investigate the risk factors of young cerebral stroke. Methods 186 cases of young cerebral stroke patients from January 2010 to June 2014 in our hospital were retrospectively analyzed, and the clini- cal characteristics and etiology were summarized and analyzed. 186 cases of healthy outpatient physical examination people were selected as control group, and the risk factors of young cerebral stroke were analyzed. Results In 186 cases pa- tients,89 cases of patients with hemorrhagic stroke and 97 cases of ischemic stroke were included, and the highest inci- dence disease were subarachnoid hemorrhage （ 19. 4% ）, basal ganglia hemorrhage （ 17. 7% ）, cerebral thrombosis （25.3%）, and brain embolism （ 14.5% ）. The main pathogenesis reasons were hypertension （42.5%）, atherosclerosis （17.7%） ,and cerebral aneurysms（9.7% ）. Univariate and Logistic analysis showed that hypertension,high cholesterol, stroke family history,migraine,smoking,and drinking were the risk factors young cerebral stroke. Conclusion The inci- dence of subarachnoid hemorrhage, basal ganglia hemorrhage, cerebral thrombosis, and brain embolism were the highest. Hypertension, atherosclerosis, and cerebral aneurysm were the major reasons of young cerebral stroke, and the hyperten- sion, high cholesterol, stroke family history, migraine headaches, smoking, and drinking were the risk factors young cerebral stroke.