内毒素和C反应蛋白检测在儿科急性呼吸道感染中的临床意义

Clinical significance of endotoxin and C-reactive protein detection for pediatric acute respiratory infection

目的:探究临床上儿科急性呼吸道感染时检测内毒素和C反应蛋白的诊断意义。方法:选取我院2012年9月-2013年9月收治的儿科急性呼吸道感染患者310例作为治疗组,并检测患者的内毒素及C反应蛋白的水平变化;同时,选取110名正常健康儿童作为对照组。结果:通过对两组儿童进行对比,急性呼吸道感染儿童的血清内毒素水平以及C反应蛋白水平均高于正常儿童,且血清内毒素水平低于C反应蛋白水平,两组差异具有统计学意义(P<0.05)。通过实验得出,细菌性感染患者的血清内毒素水平和C反应蛋白水平高于病毒性感染患者,两组差异比较具有统计学意义(P<0.05)。结论:内毒素和C反应蛋白检测对儿童急性呼吸道感染中具有重要一定的临床价值,对于病毒性感染和细菌性感染的区别也具有重要的指导意义。

Objective：To explore Clinical significance of endotoxin and C-reactive protein detection for pediatric acute respiratory infection. Methods： 310 cases of respiratory tract infection as treatment group detect changes at the patient＆#39;s level of endotoxin and C-reactive protein;at the same time, 110 healthy children as the control group. Results：endotoxin levels and C-reactive protein levels were higher than normal children, and serum endotoxin level was less than C-reactive protein levels （P〈0.05）. By the experiment, in bacterial infections patients serum endotoxin levels and C-reactive protein levels was higher than viral infection patients （P〈0.05）. Conclusion：C-reactive protein and endotoxin detection has important clinical value in children with acute respiratory infections,distinction of viral infections and bacterial infections also has important significance.