麻杏苡甘汤化裁辨治湿热郁肺证咳嗽变异性哮喘的临床研究

Clinical research on treating variant asthma with the Maxing Yigan decoction

目的:观察麻杏苡甘汤化裁辨治湿热郁肺证咳嗽变异性哮喘的临床效果。方法:将68例湿热郁肺证咳嗽变异性哮喘患者随机分为对照组和治疗组各34例。对照组患者给予沙丁胺醇气雾剂吸入治疗;治疗组患者则给予麻杏苡甘汤化裁治疗,1剂/d,2周为1个疗程,连续治疗2个疗程。治疗后观察患者临床症状改善情况,计算有效率;用肺功能检测仪对治疗前后肺功能进行检测。结果:两组患者经治疗后咳嗽、胸闷痞满、口干黏腻、便溏、头身困重等临床症状好转明显,治疗组的有效率为91.2%,明显高于对照组67.6%的有效率,差异性显著(P<0.05);两组患者肺功能经治疗后改善明显,与肺功能密切相关的第1秒用力呼气容积(FEV1)、用力肺活量(FVC)及最大呼气峰流速百分比(PEF%)等指标较治疗前改善明显,治疗组改善更为突出,差异性显著(P<0.05)。结论:麻杏苡甘汤化裁而成的中药汤剂的应用能明显改善湿热郁肺证咳嗽变异性哮喘患者的临床症状,改善肺功能,疗效确切,值得临床广泛推广。

Objective： To observe the Maxing Yigan decoction for variant asthma. Methods： 68 patients were randomly divided into a control group and the treatment group 34 cases. In the treatment group were treated with the Maxing Yigan decoction, 1 cure per day, two weeks for a course, two courses. Results： The two groups of patients after treatment of cough, chest tightness, fullness, dry mouth, sticky, loose stools, head and body weight difficulties and other clinical symptoms improved significantly, efficacy in the treatment group was 91.2%, significantly higher than 67.6% （P〈0.05）; In the two groups, patients after treatment lung function improved significantly. Conclusion： the Maxing Yigan decoction can significantly improve cough variant asthma symptoms, improve lung function, efficacy, is worthy of wider promotion.