血必净注射液治疗挤压综合征并肾功能衰竭的效果观察

Efficacy of Xuebijing injection in the treatment of crush syndrome and renal failure

目的:观察血必净注射液对挤压综合征并肾功能衰竭的临床治疗效果。方法:将28例挤压综合征并肾功能衰竭患者随机分为两组,每组14例。对照组给予常规内外科治疗,观察组在对照组基础上注射血必净。治疗前后监测两组肾功能指标水平,并观察两组疗效。结果:治疗后,两组尿量提升至正常水平,24h UP、SCr、BUN、血β2-MG水平明显降低(P<0.05),观察组24h UP、SCr、BUN、血β2-MG水平显著低于对照组(P<0.05)。观察组总有效率为92.9%,显著高于对照组的78.6%(P<0.05)。结论:血必净注射液可以明显提高挤压综合征并肾功能衰竭的治疗效果,降低死亡率,值得临床推广。

Objective：To investigate the efficacy of Xuebijing injection in the treatment of crush syndrome and renal failure. Methods： 28 cases of crush syndrome and renal failure were randomly divided into two groups, 14 cases in each group. The control group was given conventional surgical treatment, and observation group was given Xuebijing injection based on control group. Before and after treatment, renal function levels of groups were detected, and the efficacy of two groups were observed. Results ： After treatment, the 24h UP, SCr, BUN, serum ~32-MG levels of two groups were significantly reduced （P〈0.05）,and 24h UP, SCr, BUN, serum 132-MG levels of observation group were significantly lower than control group （P〈0.05）. The total effective rate of observation group was 92.9%, which was significantly higher than control group （78.6%） （P〈0.05）. Conclusion： Xuebijing injection can significantly improve the efficacy of the crush syndrome and renal failure, reducing mortality, worthy of clinical application.