我院244例药品不良反应报告分析

Analys is and evaluation of 140 ADR cases in our hospital

目的:了解广西柳州市工人医院药品不良反应(Adverse drug reaction,ADR)发生的一般规律和特点,促进合理用药。方法:回顾性分析我院2013年度所有的ADR报告,从发生ADR的年龄构成比、给药途径、严重程度及分级、科室分布、药品种类及发生频率等方面进行评价,并将我院情况与北京市某三甲综合医院和某三甲肿瘤专科医院年度ADR报告进行比较。结果:我院244例ADR报告中,以抗肿瘤药物和抗感染药物为主;静脉给药较易引发ADR,占ADR总数的98.4%;药师参与报告的例数较多,占49.59%,参与比较的医院当中,男女差异不大,年龄分布较广,医生上报的数量较多,科室分布较平均。结论:提高临床科室对ADR监测的重视和认识,普及ADR知识,进一步完善各项制度,及时客观上报,保障患者的用药安全。

Objective：To review the characteristics and the regular of adverse drug reaction （ADR） in our hospital, Promote rational drug use in clinic.Method： All of ADR cases had beencollected in 2013,which were retrospectively analyzed in patients＇ age,routes of administration,serious degrees of ADR, types of drugs ,and source of reports,compare with a general hospital and a cancer hospital in Beijing.Resuh： Among the 244 ADR cases,induced mostly by antitumor drugs and anti-infective drugs,by intravenous administration （98.4%）, and reported mostly by pharmacist （49.59%）. Conclusion： More attention should be paid to strengthen ADR monitoring and reporting, in order to improve medication safety.