期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

分化抗原簇蛋白133在乙型肝炎病毒相关肝脏良恶性病变中的表达及其与HBx蛋白的关系 被引量：5

原文传递
导出
摘要 分化抗原簇蛋白133（CD133）,又名Prominin-1、AC133,是近年发现的肝癌干细胞标志物[1].目前虽有大量文献显示,CD133在肝癌组织中高表达且与肝癌患者预后密切相关,但是其在肝癌发生前的表达状况及其在肝癌中高表达的原因尚不清楚[1-2].
作者 吴超 何前进 李常海 黄涛
机构地区 山东省莒南县人民医院普外科 黄冈市中心医院普外科 华中科技大学同济医学院附属同济医院 武汉科技大学附属天佑医院儿科
出处 《中华肝胆外科杂志》 CAS CSCD 北大核心 2015年第4期272-274,共3页 Chinese Journal of Hepatobiliary Surgery
关键词 HBX蛋白 分化抗原簇 乙型肝炎病毒 良恶性病变 肝脏 干细胞标志物 肝癌患者 AC133
分类号 R512.62 [医药卫生—内科学]
  • 相关文献

参考文献12

  • 1Ma S. Biology and clinical implications of CD133 ( + ) liver can- cer stem cells[J]. Exp Cell Res, 2013,319(2) :126-132.
  • 2郭哲,向邦德,黎乐群,曾丽霞,高军平.肝细胞癌CD133、CD90、EpCAM的表达及临床意义[J].中华肝胆外科杂志,2013,19(8):629-630. 被引量：8
  • 3Yang S, Pan X, Xiong Z, et al. The influence of hepatitis B virus X protein on the clock genes in liver cells and its significance[ J]. Chin Ger J Clin Oncol, 2011,10(8) :468-471.
  • 4吴震峰,张海斌,杨宁,杨广顺.慢性乙型肝炎病毒感染与肝内胆管细胞癌的发病及其预后的相关性研究进展[J].中华肝胆外科杂志,2013,19(11):873-877. 被引量：8
  • 5Liu Q, Chen J, Liu L, et al. The X protein of hepatitis B virus in- hibits apoptosis in hepatoma cells through enhancing the methio- nine adenosyhransferase 2A gene expression and reducing S-adeno- sylmethionine production [ J ]. J Biol Chem, 2011,286 ( 19 ) : 17168-17180.
  • 6Fang X, Dong W, Thornton C, et al. Benzo(a) pyrene induced glycine N-methyltransferase messenger RNA expression in Fundu- Ins heteroclitus embryos [ J ]. Mar Environ Res, 2010,69 (Suppl) : S74-S76.
  • 7Yang SL, Yu C, Jiang JX, et al. Hepatitis B virus X protein dis- rupts the balance of the expression of circadian rhythm genes in hepatocellular carcinoma[J]. Oncol Lett,2014,8(6) :2715-2720.
  • 8Miraglia S, Godfrey W, Yin AH, et al. A novel five-transmem- brahe hematopoietie stem cell antigen: isolation, characterization, and molecular cloning [ J ]. Blood, 1997,90 ( 12 ) : 5013-5021.
  • 9Kohga K, Tatsumi T, Takehara T, et al. Expression of CD133 confers malignant potential by regulating metalloproteinases in human hepatoeellular carcinoma [ J ]. J Hepatol, 2010, 52 ( 6 ) : 872-879.
  • 10吴超,张金玲,杨盛力,赵志辉.肝癌干细胞标志物最新进展[J].肝胆外科杂志,2013,21(4):309-311. 被引量：3

二级参考文献42

  • 1Yi-Yin Jan,Chun-Nan Yeh,Ta-Sen Yeh,Tse-Ching Chen.Prognostic analysis of surgical treatment of peripheral cholangiocarcinoma: Two decades of experience at Chang Gung Memorial Hospital[J].World Journal of Gastroenterology,2005,11(12):1779-1784. 被引量：17
  • 2Zhen-Liang Qu,Sheng-Quan Zou,Nai-Qiang Cui,Xian-Zhong Wu,Ming-Fang Qin,Di Kong,Zhen-Li Zhou.Upreguiation of human telomerase reverse transcriptase mRNA expression by in vitro transfection of hepatitis B virus X gene into human hepatocarcinoma and cholangiocarcinoma cells[J].World Journal of Gastroenterology,2005,11(36):5627-5632. 被引量：21
  • 3Zhu Z, Hao X, Yan M, et al. Cancer stem/progenitor eels are highly enriched in CD133-CD44- population in hepato cellular carcinoma. [J]. Int J Cancer, 2010,126 : 2067-2078.
  • 4Yang Z F, Ho D W, Ng M N, et al. Significance of CDg cancer stem cells in human liver cancer[J]. Cancer Cell, 2008, 18:153-166.
  • 5Yamashita T, Ji J, Budhu A, et al. EpCAM positive hepato cellular carcinoma ceils are tumor-initiating cells with stem/ progenitor cell features[J]. Gastroenterology, 9009, 136= 1012-1024.
  • 6Clarke MF, Fuller M. Stem cells and cancer: two faces of eve. Cell, 2006,124(6) :1111-1115.
  • 7Lapidot T, Sirard C, Vormoor J, et al, A cell initiating human acute myeloid leukaemia after transplantation into SCID mice. Nature, 1994, 367(6464) :645 -648.
  • 8Singh SK, Hawkins C, Clarke ID, et a1. Identification of human brain tumour initiating cells. Nature,2004,432(7015) :396 -401.
  • 9Ricci- Vitiani L, Lombardi DG, Pilozzi E, et al. Identification and ex?pansion of human colon-cancer-initiating cells. Nature, 2007 , 44S (7123) :111-115.
  • 10Yamashita T , Ji J , Budhu A, et al. EpCAM -positive hepatocellular car?cinoma cells are tumor-initiating cells with stem/progenitor cell fea?tures. Gastroenterology ,2009,136: 1012 - 1024.

共引文献16

同被引文献58

引证文献5

二级引证文献7

中华肝胆外科杂志
2015年 第4期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部