摘要
目的调查分析北京地区无偿献血人员的人巨细胞病毒(human cytomegalovirus,HCMV)流行情况,从而推动HCMV筛选在输血事业中的发展。方法随机筛选1 696例北京市无偿献血者血液样本,ELISA方法检测人巨细胞病毒免疫球蛋白G(HCMV-IgG)和人巨细胞病毒免疫球蛋白M(HCMV-IgM),并对献血者的性别、年龄、学历、职业与HCMV感染率间的关系使用SPSS 21.0软件进行了χ2检验,P<0.05为差异有统计学意义。结果北京地区无偿献血者HCMV-IgM、HCMV-IgG阳性率分别为2.12%和91.86%,不同性别、不同年龄及不同职业的无偿献血者HCMV-IgG阳性率差异有统计学意义,不同年龄的献血者HCMV-IgM阳性率差异有统计学意义。结论北京市无偿献血人群HCMV感染率与我国其他地区的数据略有不同,说明我国不同地区HCMV感染率存在一定差异。性别、年龄、职业等是导致献血者HCMV感染率存在差异的因素。
Objective To study human cytomegalovirus（HCMV）prevalence among voluntary blood donors in Beijing area of China. Methods A total of 1 696 voluntary blood donations were randomly chosen in Beijing area of China;anti-HCMV-IgM and IgG were tested by ELISA.The association between prevalence rate and the demographic characteristics such as gender,age,education,and occupation were analyzed. Results The positive rates of anti-HCMV-IgM,anti-HCMV-IgG among voluntary blood donors in Beijing area were 2.12%and 91.86%.There were significant differences of positive rates of HCMV-IgG at gender,age,and occupation.In addition,significant difference of HCMV-IgM positive rate was also observed in HCMV-IgM levels between ages. Conclusions The positive rate of HCMV-IgM and IgG in voluntary blood donors in Beijing area of China was different from other areas of China.
出处
《中国病毒病杂志》
CAS
2015年第2期136-138,共3页
Chinese Journal of Viral Diseases
基金
北京市科技工作基础专项(2013004)
关键词
献血者
人巨细胞病毒
Voluntary blood donors
Human cytomegalovirus（HCMV）
