年龄和体重指数对中青年男性骨密度的影响

The effect of age and body mass index on bone mineral density in young and middle-aged males

目的探讨年龄和体重指数对中青年男性的腰椎2-4（L2-4）和股骨颈（Neck）、大转子（Troch）、粗隆间（Inter Tro）骨密度（BMD）的影响。方法以我院322名年龄20-50岁的中青年男性为研究对象,记录年龄,测量身高、体重,计算体重指数将研究对象分为正常组、超重组和肥胖组,采用双能X线骨密度仪检测腰椎、股骨颈、大转子、粗隆间的骨密度,分析年龄和体重指数与各部位骨密度变化的关系。结果中青年男性各部位的骨密度随体重指数的增加而增高。肥胖组和超重组各部位骨密度均比正常组高（P〈0.05或P〈0.01）。20-29岁组的骨密度明显高于30-39岁组和40-50岁组（P〈0.01）。结论年龄和体重指数是影响骨密度的重要因素,体重指数与中青年男性不同部位的骨密度存在一定的相关性,肥胖者及超重者骨密度较正常体型者高,因此,适量增加体重可以提高人体骨密度,对预防骨质疏松症将有着重要的作用。

Objective To explore the effect of different age and body mass index （BMI） on bone mineral density （BMD） of the lumbar spine （L2-4） , the femoral neck （Neck） , the greater trochanter （Troch）, and the intertrochanter （InterTro） in young and middle-aged males. Methods The research subjects were 322 males from 20 to 50 years old. Age was recorded. Height and weight were measured. BMI was calculated. The subjects were divided into the normal group,the overweight group, and the obese group according to BMI. BMD of the lumbar spine, the femoral neck, the greater trochanter, and the intertrochanter were measured using dual energy X-ray absorptiometry. The relationship between age, BMI, and BMD of different sites were analyzed. Results The BMD of different sites in young and middle-aged males increased with the increase of BMI. ,The BMD of different sites in the obese group and overweight group was higher than those in the normal group （ P 〈 0. 05 or P 〈 0.01 ）. BMD in the 20 - 29 years old group was significantly higher than that in the 30 - 39 years old group and 40 - 50 years old group （P 〈 0.01 ）. Conclusion Age and BMI are important factors for BMD. BMI is certainly related to the BMD of different sites in young and middle-aged males. BMD of subjects in the obese group and the overweight group are significantly higher than those in the normal group. Therefore, improvement of BMD through a modest increase of weight plays an important role in the prevention of osteoporosis.