致眼部感染病原菌及其耐药性分析

Ophthalmic infection associated pathogenic bacteria and their drug resistance

目的探讨眼部感染患者的病原菌组成及其耐药性。方法选取2010年1月至2014年6月就诊于温州医科大学附属眼视光医院的眼部感染患者,对临床送检的标本进行鉴定培养。培养阳性的菌株经API或ATB试剂条鉴定,并对标本进行分类及药物敏感性分析。结果阳性细菌610株,以革兰阳性球菌为主,占69.84%,革兰阴性杆菌次之,占16.89%;真菌115株,以镰刀菌属为主,占43.48%。万古霉素、夫西地酸、左氧氟沙星等对大部分菌株有较好的敏感性。结论掌握眼科感染病原菌分布及药物敏感性规律,可有效预防和控制眼部感染。

Objective To investigate the distribution and drug resistance of pathogens from patients with ophthalmic infections in our hospital. Methods The clinical samples were collected from patient with eye infections in the Affiliated Eye Hospital of Wenzhou Medical University during Jan. 2010 and Jun. 2014, which were cultured and identified by API or ATB strips and then classified. The drug sensitivity of the pathogens were analyzed. Results A total of 610 strains of bacteria were isolated, among which Gram-positive cocci accounted for 69. 84%, Gram- negative bacilli 16. 89%. In the 115 strains of fungi, fusarium was the main pathogen which accounted for 43.48%. Most of the strains showed a high sensitivity to vancomycin, fusidic acid and levofloxacin, etc. Conclusion By learning the distribution and drug sensitivity of the pathogens, we can effectively prevent and control eye infections.