摘要
目的了解深圳市福田区轮状病毒的感染情况,为制定预防轮状病毒感染的策略提供依据。方法采用实时荧光定量聚合酶链反应（real-time PCR）对2011—2013年深圳市福田区1728例疑似病毒性腹泻患者粪便标本进行轮状病毒的核酸检测。结果 2011—2013年福田区轮状病毒的总体检出率为18.29%（316/1728）,2011—2013年检出率起伏较大,分别为22.16%（115/519）、13.13%（73/556）和19.60%（128/653）;男性检出率为18.53%（184/993）,女性检出率为19.96%（132/735）;轮状病毒在冬季的检出率最高（34.79%,167/480）,秋季次之（20.67%,87/421）,春季、夏季的检出率较低。0~5岁年龄组患者的检出率（21.01%,232/1104）显著高于5岁以上年龄组患者的检出率（13.46%,84/624）,差异有统计学意义,（χ2=29.5786,P〈0.05）。结论轮状病毒是福田区病毒性腹泻的重要病原体之一,2011—2013年检出率呈较大起伏;冬季是轮状病毒感染的高发季节;0~5岁婴幼儿患者是轮状病毒感染的重点人群;应加强对轮状病毒腹泻的监测,尤其应加强对婴幼儿轮状病毒感染的预防控制。
Objective To investigate the infection status of rotavirus in Futian district of Shenzhen, Guangdong province, and provide evidence for the prevention and treatment of diarrhea. Methods Stool samples were collected from suspected viral diarrhea patients in Futian. Rotaviruses were detected by using real time polymerase chain reaction （real-time PCR）. Results From January 2011 to December 2013, a total of 1728 stool samples were collected, the overall detection rate of rotavirus was 18. 29% （316/1728）, while the annual detection rates were 22. 16% （115/519）, 13.13% （73/556）, and 19. 60% （128/653） respectively. The detected rate of rotavirus was 18.53% among males （184/993） and 19. 96% among females （132/735）. The detection rate was highest in winter（34. 79%, 167/480）, followed by autumn（20. 67%, 87/421 ）, while the detection rate was low in spring and summer. The detection rate was significantly higher in age group 0 - 5 years（21.01% ） than in age group 〉 5 years（ 13.46% ）. Conclusion Rotavirus was one of the major pathogens causing viral diarrhea in Futian district, while the detection rates showed marked fluctuation from 20l 1 to 2013. The rotavirus infection had obvious seasonality with incidence peak in winter. Infants and young children were more susceptible. Therefore, it is necessary to strengthen the prevention and control of viral diarrhea caused by rotavirus, especially among infants and young children.
出处
《疾病监测》
CAS
2015年第4期284-286,共3页
Disease Surveillance
