动脉硬化性脑梗死的危险因素分析

Analysis of Risk Factors of Cerebral Infarction Atherosclerosis

目的探讨动脉硬化性脑梗死的危险因素。方法选择2013年1月~2014年12月住院且发病14天内的动脉硬化性脑梗死137例为病例组,纳入同期住院治疗的192例非心脑血管患者为对照组,同时记录两组纳入者的基本情况及脑血管病相关危险因素,测定患者的空腹血糖,尿素氮,肌酐,尿酸,血浆纤维蛋白原,HCY,血脂水平,收缩压,舒张压,颈动脉彩超测定有无动脉硬化及斑块形成,并进行统计学分析。结果单因素分析表明：两组间高血压,颈动脉硬化,吸烟,GLU,HCY,CHO,HDL,LDL,收缩压,舒张压的差异有统计学意义（P〈0.05）。LOGISTIC回归分析显示：年龄,高血压,颈动脉硬化,吸烟,LDL,收缩压与动脉硬化性脑梗死有关（P〈0.05）。结论动脉硬化性脑梗死患者的高危因素进行筛查和干预,对缺血性脑卒中的预防和治疗有重要的意义。

Objective To investigate the risk factors of arteriosclerotic cerebral infarction. Methods Choose 2013 January -2014 December in Wuhan City fourteenth Hospital Department of internal medicine hospital arteriosclerotic cerebral infarction onset within 14 days of the 137 patients included, 192 hospitalized non cardiovascular patients as con- trol group, two groups of related risk also recorded into the basic situation and cerebral vascular disease factors for deter- mination of fasting blood glucose, blood urea nitrogen, ereatinine, uric acid, patients, plasma fibrinogen, HCY, blood lipid level, systolic blood pressure, diastolic blood pressure, carotid artery color Doppler ultrasound to determine the presence or absence of atherosclerosis and plaque formation, and carries on statistics analysis. Results Single factor a- nalysis showed that： two groups of hypertension, carotid artery atherosclerosis, smoking, GLU, HCY, CHO, HDL, LDL, systolic pressure, diastolic pressure difference has statistics significance （P 〈 0. 05 ）. LOGISTIC regression analysis showed： age, hypertension, carotid artery atherosclerosis, smoking, LDL, systolic blood pressure andarteriosclerotic cer- ebral infarction （P 〈 0.05 ）. Conclusions Dynamic risk factor for patients with arteriosclerosis cerebral infarction for screening and intervention, have important significance for prevention and treatment of ischemic stroke.