抗生素联合糖皮质激素治疗老年慢性阻塞性肺气肿疗效分析

Analysis of Antibiotic and Corticosteroid in the Treatment of Elderly Patients with Chronicobstructive Pulmonary Emphysema

目的探讨抗生素联合糖皮质激素治疗老年慢性阻塞性肺气肿的临床疗效。方法选取2012年8月~2014年8月治疗的54例慢性阻塞性肺气肿患者,随机分为观察组和对照组,各26例,均进行吸氧、支气管扩张、祛痰和抗生素等基础治疗,观察组在基础治疗方式上采用泼尼松进行治疗。结果治疗后,观察组的总有效率（80.43%）明显高于对照组（93.48%）,观察组病人不良反应发生率（6.52%）明显低于对照组（13.04%）,（P〈0.05）。结论抗生素联合糖皮质激素治疗老年慢性阻塞性肺气肿,疗效显著,安全性高。

Objective To explore the clinical curative effect in treating senile chronic obstructiveemphysema of anti- biotics combined with glueocorticoid. Methods From 2012 August ~ 2014 year in August in 54 cases of chronic obstruc- tive emphysema patients treated in our hospital, were randomly divided into observation group and control group, each 26 cases, wereoxygen, bronchiectasis, expectorant and antibiotics in foundation treatment, the observation group based on treatment with prednisone treatment on. Results After treatment, the totaleffieieney of the observation group （80.43%） was significantly higher than the control group （93. 48% ）, adverse reactions observed group of patients the incidence （6. 52% ） was significantly lower than the control group （ 13.04% ）, （P 〈 0. 05 ）. Conclusions Antibiotics combined with glueocortieoid in treatment of elderly patients with chronic obstructive pulmonary emphysema, obvious curative effect, high safety.