摘要
目的 :探讨直肠癌异时性单纯肺转移的的预后影响因素及其治疗方案。方法:回顾性分析2007年6月—2011年12月收治的14例直肠癌术后发生异时性单纯肺转移患者的临床及随访资料,分别用Log-rank检验和C ox风险模型对其临床资料进行单因素和多因素的分析。结果:14例异时性单纯肺转移患者中单侧肺转移11例,双侧肺转移3例。单因素分析显示,术后辅助化疗、肿瘤大体分型、清除淋巴结数目、淋巴结是否转移以及TN M分期与直肠癌患者异时性肺转移的发生有相关性,是其危险因素(P<0.05)。多因素分析示,TN M分期以及淋巴结转移与直肠癌术后异时性肺转移的发生具有独立相关性(P<0.05)。结论:TN M分期和淋巴结有转移是影响直肠癌患者发生异时性肺转移的重要因素。
Objective： To explore the prognostic analysis of risk factors and treatments in metachronous pulmonary metastasis after curative resction of rectal cancer. Methods： Clinical data of 14 patients with rectal cancer who underwent radical operation in Chinese PLAG eneral Hospital fromJun 2007 to Dec 2011 were retrospectively analyzed by univariate and multivariate analysis.Result： Univariate analysis identified adjuvant chemotherapy,gross type of tumor, examined lymph nodes, lymph nodes metastasis and TNM stage had effects on metachronous pulmonary metastasis.Multivariate analysis showed that TNM stage, adjuvant chemotherapy and lymph nodes metastasis are the independentfactors for the lung metastasis. Conclusion： The TNM stage and lymph nodes metastasis are important factors associated with the risk of lung metastasis fromrectal cancer in patients after curative resction.
出处
《中国现代普通外科进展》
CAS
2015年第3期206-209,共4页
Chinese Journal of Current Advances in General Surgery
基金
国家自然基金面上项目(61170123
60601018)
海南省自然科学基金(813226)
关键词
直肠肿瘤
肺转移
异时性
危险因素
Rectal cancer
Pulmonary metastasis
metachronous
Risk factors
