相位对比法磁共振成像测量主动脉和肺动脉起始部净血流量的准确性研究

Measurement Accuracy of Net Blood Flow Volume of the Initial Part of Aorta and Main Pulmonary Artery by Using PC MRI

目的采用相位对比法(PC)磁共振成像(MRI)测量健康志愿者的主、肺动脉起始部净血流量,并进行比较,以验证PC MRI测量主、肺动脉起始部净血流量的准确性及可重复性。方法选取2012年1月—2013年12月昆明医科大学第二附属医院进行体检的健康志愿者31例,采用PC MRI测量心动周期内主、肺动脉起始部净血流量,观察PC MRI测量主、肺动脉起始部净血流量的准确性;前后两次测量9例健康志愿者主、肺动脉起始部净血流量,观察PC MRI测量主、肺动脉起始部净血流量的可重复性。结果主、肺动脉起始部时间-净血流量图呈逐渐上升曲线,相对应心脏的收缩期,主、肺动脉起始部净血流量曲线表现为倾斜度较大、光滑且连续的曲线;相对应心脏的舒张期,主、肺动脉起始部净血流量曲线表现为逐渐向上、波形较平缓、光滑且连续的曲线。主动脉起始部净血流量(72.8±12.2)ml,肺动脉起始部净血流量(73.8±13.8)ml,差异无统计学意义(t=-1.924,P=0.64)。主动脉起始部净血流量与肺动脉起始部净血流量呈正相关(r=0.94,P<0.05),方程为:Y=-3.825+1.066X。第1次与第2次测量主、肺动脉起始部净血流量比较,差异均无统计学意义(P>0.05)。第1次与第2次测量主动脉起始部净血流量呈正相关(r=0.91,P<0.05),方程为:Y=-6.669+1.078X。第1次与第2次测量肺动脉起始部净血流量呈正相关(r=0.92,P=0.001),方程为:Y=5.391+0.923X。结论 PC MRI是一种无创、安全、准确、信息量大的检查方法,且不受肺气、骨骼的影响,是研究主、肺动脉起始部净血流量的好方法。

Objectjve In order to evaluate the accuracy and repeatability of PC MRI in measuring the net blood flow volume of aorta and main pulmonary artery,the net blood flow volume of aorta and main pulmonary artery is measured by using PC MRI among healthy volunteers,the results were compared. Methods 31 healthy volunteers who received health examination in the Second Affiliated Hospital of Kunming Medical University from January 2012 to December 2013,were selected as study subjects,the net blood flow volume of the initial part of aorta and pulmonary artery in the cardiac circle was measured by using PC MRI,the accuracy of PC MRI in measuring the net blood flow volume was analyzed. To find out the measurement repeatability of net blood flow volume of aorta and main pulmonary artery by using PC MR,the net blood flow volume of aorta and pulmonary artery is measured by using PC MRI among 9 healthy volunteers twice. Results The time - net blood flow volume diagram for the initial part of aorta and pulmonary artery showed a rising curve. In systole,the time - net blood flow volume diagram for the initial part of aorta and pulmonary artery showed a smooth,continuous curve with high inclination;in diastole,the time - blood flow volume diagram for the initial part of aorta and pulmonary artery showed a smooth,continuous and rising curve with mildnbsp;waveform. There was no significant difference in the net blood flow volume between the initial part of aorta artery〔（72. 8 ± 12. 2） ml〕and the initial part of pulmonary artery〔（73. 8 ± 13. 8）ml〕（t = - 1. 924,P = 0. 64）. The net blood flow volume of aorta was positively correlated with the net blood flow volume of main pulmonary artery（ r = 0. 94,P 〈 0. 05）,the equation：Y= - 3. 825 ＋ 1. 066X. There was no significant difference in the net blood flow volume of aorta and main pulmonary artery between the first time and the second time（P 〉 0. 05）. The net blood flow volume of aorta for the first time was positively correlated with the net blood flow volume of aorta for the second time（r = 0. 91,P 〈 0. 05）,the equation：Y = - 6. 669 ＋ 1. 078X. The net blood flow volume of main pulmonary artery for the first time was positively correlated with the net blood flow volume of main pulmonary artery for the second time（r = 0. 92,P = 0. 001）,the equation：Y = 5. 391 ＋ 0. 923X. Conclusjon PC MRI is a noninvasive,safe,accurate and informative method, and is not affected by air and bone, so it is a good method for hemodynamic study of aorta and pulmonary artery.