微生态制剂对预防肝硬化自发性腹膜炎再发的疗效观察及护理体会

Therapeutic effects of microecologics for the prevention of recurrence of spontaneous bacterial peritonitis in liver cirrhosis patients: an observation and nursing experience

目的探讨常规保肝基础上联合微生态制剂对肝硬化自发性腹膜炎再发的疗效及护理措施。方法选取选取2011年10月至2013年6月来我院治疗的肝硬化自发性腹膜炎患者48例,随机分为微生态治疗组及对照组,微生态治疗组行常规保肝治疗并加用微生态制剂,对照组仅行常规保肝治疗,比较1年内两组患者自发性腹膜炎的再发情况及再发时各症状缓解时间的变化,并总结护理措施。结果微生态治疗组再发率明显低于与对照组再发率,差异有统计学意义(P<0.05);微生态治疗组的各项症状的缓解时间也明显少于对照组,差异有统计学意义(P<0.05)。结论在常规保肝基础上加服微生态制剂可以有效地预防肝硬化患者自发性腹膜炎再发,并能显著缩短再发时各症状的缓解时间。同时,护理人员的正确护理是保证治疗顺利进行,并改善患者预后的关键。

Objective To explore the therapeutic effects of microecologies combined with routine treatment for the prevention of recurrence of spontaneous bacterial peritonitis in liver cirrhosis patients, and discuss the nursing expe- rience. Methods 48 liver cirrhosis patients with spontaneous bacterial peritonitis were randomly divided into con- trol group and microeeologics group （24 cases in each group）. The patients in control group were treated with rou- tine hepatoprotective drug, while those in mieroecologics group were administered Peifeikang orally on the basis of the hepatoproteetive drug. The course of the treatment was 3 months. The recurrence of spontaneous bacterial peri- tonitis and the remission time for the symptoms within one year were recorded, and the nursing measures were re- viewed. Results Incidence of spontaneous bacterial peritonitis in microecologies group were significantly lower than that in the control group （ P 〈 0. 05 ）. Conclusion Mieroecologics treatment on the basis of routine hepato- protective medication can significantly reduce the recurrence rate of spontaneous bacterial peritonitis in liver cirrho- sis patients, and shorten the time to remission of the symptoms. Meantime, correct nursing measures are the key to guarantee a better prognosis.