二乙酰氨乙酸乙二胺联合垂体后叶素治疗支气管扩张并咯血的疗效观察

Efficacy Observation of Ethylenediamine Diaceturate and Pituitrin in the Treatment of Patients with Bronchiectasis Hemoptysis

目的:主要观察二乙酰氨乙酸乙二胺联合垂体后叶素对支气管扩张并咯血的疗效。方法:选取2012年1月-2014年6月在我院就诊的支气管扩张并咯血患者84例,随机分为观察组(n=42)和对照组(n=42),两组均常规抗感染、体位引流、垂体后叶素持续泵入等治疗,在此基础上观察组给予二乙酰氨乙酸乙二胺(0.6g/d)静滴治疗;对照组给予酚磺乙胺(3g/d)静滴治疗,治疗结束时比较两组的疗效及不良反应。结果:观察组总的有效率为95.24%,对照组总的有效率为78.57%,两者比较,P<0.05,差异有统计学意义;观察组不良反应发生率为28.57%,对照组不良反应为35.71%,两者比较,P>0.05,差异无统计学意义。结论:在基层医院,二乙酰氨乙酸乙二胺联合垂体后叶素持续泵入治疗支气管扩张并咯血疗效确切,副作用小且易控制,故值得尝试使用。

Objective ：To observe efficacy of ethylenediamine diaceturate and pituitrin in the treatment of patients with bronchiectasis hemoptysis .Methods ：84 cases of patients with bronchiectasis hemoptysis were chosen between January 2012 to June 2014 in our hospital ,were randomly divided into observation group （n= 42） and control group （n= 42） . Two groups were given all routine anti‐infection ,postural drainage ,pituitrin treatment by continuous pumping ,on the basis of which the observation group was given ethylenediamine diaceturate （0 .6g/d） ;the control group were given eta‐msylate （3g/d） .Efficacy and adverse reactions of two groups were compared at the end of the treatment .Results ：The total effective rate of observation group was 95 .24% ,the total effective rate of control group was 78 .57% ,P〈 0 .05 , there was statistical significance between two groups ;adverse reactions rate of observation group was 28 .57% ,adverse reaction rate of control group was 35 .71% ,P〉 0 .05 ,there was no statistical significance between two groups .Conclu‐sion ：In grass‐roots hospitals ,curative effect of ethylenediamine diaceturate and pituitrin in the treatment of patients with bronchiectasis hemoptysis is obvious ,and side effect is small and easy to control ,so it is worth trying to use .