吴茱萸碱诱导肿瘤细胞凋亡的分子机制研究进展

Molecular mechanism of tumor cell apoptosis induced by evodiamine

吴茱萸碱(evodiamine,Evo)是中药吴茱萸重要的生物碱成分之一,具有良好的抗肿瘤活性。目前的研究表明,吴茱萸碱抗肿瘤作用主要通过诱导肿瘤细胞发生凋亡。本文就近几年吴茱萸碱在诱导肿瘤细胞凋亡分子机制方面的最新研究进展进行简要综述。

Evodiamine（ Evo）, an alkaloid isolated from the traditional Chinese medicine Evodiae, is a potential anti -cancer agent. It could induce apoptosis of cancer cell significantly. In this paper, we reviewed the current research progress on molecular mechanism of tumor cell apoptosis induced by Evodiamine.