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炎性细胞因子对神经干细胞增殖与分化的调节 被引量:2

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摘要 一、前言 神经干细胞(neural stem cells,NSCs)因其自我更新和多向分化能力作为新生神经细胞的有效来源为干细胞替代治疗及募集治疗中枢神经系统(central nervous system,CNS)疾病带来了曙光。体内外NSCs受诸多细胞因子调控,传统观念认为绝大多数调节NSCs的因子与免疫源性因子无关。
出处 《中华神经外科疾病研究杂志》 CAS 2015年第2期190-192,共3页 Chinese Journal of Neurosurgical Disease Research
基金 甘肃省自然科学基金资助项目(1208RJZA184)
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  • 1Kokaia Z, Martino G, Schwartz M, et al. Cross-talk between neural stem ceils and immune ceils: the key to better brain repair .9 [ J]. Nat Neurosci, 2012, 15(8) : 1078 - 1087.
  • 2Ajmone-Cat MA, Cacci E, Ragazzoni Y, et al. Pro-gliogenic effect of IL-lct in the differentiation of embryonic neural precursor cells in vitro [J]. 3 Neurochem, 2010, 113(4) : 1060 -1072.
  • 3Green HF, Treacy E, Keohane AK, et al. A role for interleukin-l~ in determining the lineage fate of embryonic rat hippocampal neural precursor cells [J]. Mol Cell Neurosci, 2012, 49(3) : 311 -321.
  • 4Zhang K, Xu H, Cao L, et al. lnterleukin-la inhibits the differentiation of hippocampal neural precursor ceils into serotonergic neurons [J]. Brain Res, 2013, 1490:193 -201.
  • 5Butovsky O, Ziv Y, Schwartz A, et al. Microglia activated by IL-4 or IFN-g differentially induce neurogenesis and oligodendrogenesis from adult stem/progenitor cells [J]. Mol Cell Neurosci, 2006, 31 ( 1 ) : 149 - 160.
  • 6Perez-Asensio FJ, Perpin6 U, Planas AM, et al. Interleukin-10 regulates progenitor differentiation and modulates neurogenesis in adult brain [J]. J Cell Sci 2013, 126(Pt 18) : 4208 -4219.
  • 7Guan Y, Jiang Z, Ciric B, et al. Upregulation of chemokine receptor expression by IL-10/IL-4 in adult neural stem cells [ J ]. Exp Mol Pathol, 2008, 85 (3) : 232 - 236.
  • 8Kiyota T, Ingraham KL, Swan ILl, et al. AAV serotype 2/1-mediated gene delivery of anti-inflammatory interleukin-10 enhances neurogenesis and cognitive function in APP + PS1 mice [J]. Gene Ther, 2011, 19 (7) : 724 -733.
  • 9Spooren A, Kolmus K, Laureys G, et al. Interleukin-6, a mental eytokine [J]. Brain Res Rev, 2011,67(1 -2) : 157 -183.
  • 10Islam O, Gong X, Rose-John S, et al. Interleukin-6 and neural stem cells: more than gliogenesis [J]. Mol Biol Cell, 2009, 20(1): 188 -199.

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