脂肪溶解液预防乳腺癌术后淋巴漏的临床效果分析

Clinical analysis of liposuction for preventing lymphatic fluid leakage after axillary lymph nodes dissection in breast cancer

目的:探讨脂肪溶解液辅助腋窝淋巴结清扫对乳腺癌术后淋巴漏发生率的影响。方法:行乳腺癌改良根治术患者86例,其中常规行乳腺癌改良根治术清扫腋窝淋巴结的52例为对照组,术中加用脂肪溶解液辅助腋窝淋巴结清扫的34例为观察组。比较2组术后3 d引流管引流量、腋窝引流管留置时间、皮下积液的发生率。结果:观察组术后第2天、第3天引流量和腋窝引流管留置时间均较对照组明显减少(P<0.01),皮下积液的发生率低于对照组(P<0.05)。结论:乳腺癌改良根治术中使用脂肪溶解液辅助腋窝淋巴结清扫可以预防术后淋巴漏的发生。

Objective：To investigate the effect of postoperative lymphatic fluid leakage after the axillary lymph nodes dissection by liposuction. Methods：Eighty-six breast cancer patients were included in this study,which were divided into two groups,the patients with dissection of axillary lymph nodes by liposuction （ n=34 ） were in observation group, and the patients with traditional axillary lymph node dissection（ n=52 ） were in control group. The draining volume in the postoperative 3 days, draining time and the incidence of subcutaneous fluid were compared between the two groups. Results：The postoperative drainage volume and drainage time in the second day and the third day in observation group were less than in control group（P 〈0. 01）. The incidence of subcutaneous fluid in observation group was lower than that in control group（P〈0. 05）. Conclusions：The axillary lymph nodes dissection by liposuction can reduce the incidence of postoperative lymphatic leakage,it can be applied widely in axillary lymph nodes dissection in breast cancer.