三维斑点追踪技术对冠心病患者PCI前后左心室壁运动的评价与分析

Application of the 3-dimensional speckle tracking imaging on the evaluation of left ventricular wall motion in patients with coronary artery disease before and after PCI

目的：应用三维斑点追踪显像技术（3D-STI）观察冠心病（CAD）经皮冠状动脉介入术（PCI）治疗前后左心室收缩功能的变化。方法：对50例CAD患者（CAD组）分别于PCI治疗前、治疗后3-7 d内、治疗后3个月时,及30名健康体检者（对照组）进行3D-STI分析,测量出左心室壁各心肌节段的圆周应变峰值（CSpeak）。结果：与对照组比较,CAD组PCI治疗前及治疗后的CSpeak均降低;与PCI治疗前比较,PCI治疗后3-7 d内的CSpeak增高;PCI治疗后3个月上述指标增高变化更为显著（P〈0.01）。结论：冠心病患者的心肌变形能力下降,经PCI治疗后可获得改善,同时3D-STI可以准确定量评价冠心病患者左心室心肌收缩功能的异常。

Objective：To observe the systolic function of left ventricular in patients with coronary artery disease（CAD） before and after the percutaneous coronary intervention（PCI） by 3-dimensional speckle tracking imaging（3D-STI）. Methods：The 3D-STI data of 50 CAD patients（ CAD group） before and after 3 to 7 days and 3 months of PCI and 30 healthy people（ control group） were analyzed. The circumferential strain peaks（ CSpeak） of each myocardial segment of left ventricular wall were measured. Results：Compared with the control group,the CSpeak in CAD group before and after PCI was decreased. Compared with before PCI,the CSpeak in CAD group after 3 to 7 days of PCI was increased. After 3 months of PCI,changes of the CSpeak in CAD group were significant（P 〈0. 01）. Conclusions：The myocardial deformation ability in patients with coronary artery disease is decreased,which can be improved after PCI. The 3D-STI can accurately assess the left ventricular systolic function in patients with coronary artery disease.