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188例次腹膜透析相关性腹膜炎细菌谱及耐药性分析 被引量:5

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摘要 目的探讨腹膜透析(continuous ambulatory peritoneal dialysis,CAPD)相关性腹膜炎的致病菌及其耐药性。方法回顾性分析郑州大学第一附属医院肾脏病研究中心2006年10月至2014年6月收治的188例次腹膜透析相关性腹膜炎患者的细菌谱、耐药性及转归。结果 188例次CAPD引流液培养中,130例次(69.15%)培养阳性,共培养病原菌131株。致病菌中革兰阳性球菌85株(64.89%);革兰阴性菌33株(25.19%);真菌13株(9.71%)。未发现对利奈唑胺、替考拉宁耐药菌株;革兰阳性菌对红霉素、青霉素的耐药率均87.06%,对万古霉素(2.35%)、亚胺培南(9.64%)的耐药率较低;革兰阴性菌对头孢唑啉耐药率为69.70%,对亚胺培南(3.03%)耐药率较低,对庆大霉素(36.36%)的耐药率有下降趋势。188例次患者治愈率82.98%。结论腹膜透析相关性腹膜炎仍以革兰阳性球菌为主;致病菌对红霉素、青霉素、头孢唑啉的耐药率较高,对亚胺培南和万古霉素的耐药率较低。
出处 《河南医学研究》 CAS 2015年第2期41-44,共4页 Henan Medical Research
基金 河南省卫生厅医学科技攻关项目(201202009)
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  • 1曹颖,赵占正,魏二虎,申万琴,刘章锁.85例次腹膜透析相关性腹膜炎的致病菌及药敏分析[J].临床荟萃,2010,25(5):405-408. 被引量:15
  • 2Campbell D J,Johnson D W, Mudge D W, et al. Prevention of perito- neal dialysis -related infections[ J]. Nephrol Dial Transplant, 2014, 10(7) : 1 - 12.
  • 3Li P K, Szeto C C, Piraino B, et al. Peritoneal dialysis - related in- fections recommendations:2010 update[ J ]. Petit Dial Int, 2010, 30 (4) : 393 - 423.
  • 4Govindarajulu S, Hawley C M, McDonald S P, et al. Staphylococcus aureus peritonitis in Australian peritoneal dialysis patients: predic- tors,treatment,and outcomes in 503 cases [ J ]. Petit Dial Int, 2010, 30(3) : 311 -319.
  • 5Furgeson S B, Teitdbaum I. New treatment options and protocols for peritoneal dialysis - related peritonitis [ J ]. Conttib Nephrol, 2009, 163(6) : 169 -176.
  • 6Szeto C C,Chow K M,Kwan B C,et al. Staphylococcus aureus peritonitis complicates peritonitis dialysis : review of 245 consecutive cases [ J ]. Clin J Am Soc Nephro1,2007,2(2) : 245 -251.
  • 7詹周兵,石永兵,沈华英,姜林森,冯胜,金东华,王峙,姜山,曾颖.236例次腹膜透析相关性腹膜炎的致病菌分布及耐药性分析[J].中华肾脏病杂志,2014,30(3):195-200. 被引量:32
  • 8Piraino B. Insight on peritoneal dialysis - related infections [ J ]. Cont- rib Nephrol Epub,2009, 16(3) : 161 -168.
  • 9Matsumoto K. The development of appropriate dosage of anti - bacteri-al and anti -fungal agents based on pharmacokinetics and pharmaco- dynamics[ J:. Yakugaku Zasshi ,2012,132(10) : 1171 - 1177.
  • 10Thompson S, Townsend R. Pharmacological agents for soft tissue and bone infected with MRSA: which agent and for how long? [ J]. Inju- ry,2011,42(5) : $7 - 10.

二级参考文献49

  • 1维持性腹膜透析共识[J].中华肾脏病杂志,2006,22(8):513-516. 被引量:96
  • 2郭群英,陈林,阳晓,杨念生,冯敏,姜宗培,毛海萍,陈崴,余学清.腹膜透析相关感染性腹膜炎致病菌及菌谱变化——单个腹膜透析中心15年回顾分析[J].中华肾脏病杂志,2006,22(12):719-724. 被引量:64
  • 3倪军,童孟立,崔杏成.72例次持续性非卧床腹透腹膜炎分析[J].中国中西医结合肾病杂志,2007,8(4):217-219. 被引量:24
  • 4Bender FH, Bernardini J, Piraino B. Prevention of infectious complications in peritoneal dialysis : best demonstrated practices[J]. Kidney Int Suppl,2006,70(103) :S44-54.
  • 5Santoianni JE,Predari SC,Veron D,et al. A 15 year-review of peritoneal dialysis-related peritonitis: microbiological trends and patterns of infection in a teaching hospital in Argentina [J]. Rev Argent Microbiol,2008,40(1) :17-23.
  • 6Piraino B. Insight on peritoneal dialysis-related infections[J]. Contrib Nephrol Epuh, 2009,16(3) : 161-168.
  • 7Shemin D. Gram negative rod peritonitis in peritoneal dialysis [J]. Semin Dial, 1997,10(1) :38-45.
  • 8Wiggins KJ, Craig JC, Johnson DW, et al. Treatment of peritoneal dialysis-associated peritonitis:a systematic review of randomized controlled trials[J]. Am J Kidney Dis, 2007, 50 (6) :967-988.
  • 9叶应抚,王毓三.全国临床检验操作规程[M].南京:东南大学出版社,1991:165-168.
  • 10Verger C, Ryckelynck JP, Duman M, et al. French peritoneal dialysis registry(RDPLF): outline and main results[J]. Kidney Int(Suppl), 2006, 103: S12-S20.

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