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胰腺癌组织HSP90α、VEGF-C蛋白表达及其临床意义 被引量:4

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摘要 胰腺癌恶性程度高、侵袭力强、进展快、预后极差.诊断后的中位生存期只有5~6个月,发病后5年生存率仅为5% ~ 10%,死亡率在各肿瘤中位居第4位.目前手术是唯一根治的方法,但有机会接受手术治疗的患者不到30%,并且术后5年的存活率也低于20%.
出处 《中华胰腺病杂志》 CAS 2015年第2期129-131,共3页 Chinese Journal of Pancreatology
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参考文献12

  • 1李凤茹,江华.胰腺癌发病的高危因素分析[J].国际消化病杂志,2013,33(5):331-334. 被引量:9
  • 2Pannala R, LeirnesslB, Bamlet WR, ei al. Prevalence and clinical profile of pancreatic cancer-associated diabetes mellitus[J] . Gastroenterology, 2008 ,134 ( 4 ) : 981-987 .
  • 3Richter A, Niedergethmann M, SturmJW, et al. Long-term results of partial pancreaticoduodenectomy for ductal adenocarcinoma of the the pancreatic head: 25-year experience[J]. World 1 Surg, 2003, 27(3) : 324-329.
  • 4胰腺癌诊治指南(2014版)[J].中华消化外科杂志,2014,13(11):831-837. 被引量:46
  • 5Sun 1, Liu L, liang X, et al. Therapeutic effects of radiolabeled 17 -allylamino-17 -demethoxygeldanamycin on human H460 nonsmall-cell lung carcinoma xenografts in mice[J]. Cancer Biother Radiopharm, 20 I 0 ,25 ( 2) : 155 -164.
  • 6BarrottJ J, Haystead TA. Hsp90, an unlikely ally in the war on cancer[J]. FEBSJ, 2013, 280(6) :1381-1396.
  • 7Xu Y, Zhong Z, Yuan 1, et al. Collaborative overexpression of matrix metalloproteinase-I and vascular endothelial growth factorC predicts adverse prognosis in patients with gliomas[J] . Cancer Epidemiol, 2013, 37(5): 697-702.
  • 8亓宪银,李大宏,徐林浩.非小细胞肺癌中VEGF-C、VEGFR-3 mRNA表达对淋巴结转移和预后的研究[J].重庆医学,2011,40(15):1478-1480. 被引量:5
  • 9张胜辉,王轶灵,王明松,曹佳,费苛,校宏兵.血管内皮生长因子表达与肺癌预后的关系[J].重庆医学,2010,39(16):2157-2158. 被引量:17
  • 10Xu W, Neckers L. Targeting the molecular chaperone heat shock protein 90 provides a multifaceted effect on diverse cell signaling pathways of cancer cells]J]. Clin Cancer Res, 2007, 13 (6) : 1625-1629.

二级参考文献55

  • 1陈公琰,洪璇.血管内皮生长因子与肺癌的关系[J].中华肿瘤杂志,2005,27(8):449-451. 被引量:27
  • 2Kar K,Kainen MJ,Petrova TV.Vascular endothelial growth factor receptors in the regulation of angiogenesis and lymphangiogenesis[J].Oncogene,2000,19(49):5598-5605.
  • 3Duff SE,Li C,Renehan AO,et al.Immunnodetection and molecular forms of plasma vascular endothelial growth factor-C[J].Int J Oncol,2003,22(2):339-343.
  • 4Tanigaki Y,Nagashima Y,Kitamura Y,et al.The expression of vascular endothelial growth factor-A and -C,and receptors 1 and 3:correlation with lymph node metastasis and prognosis in tongue squamous cell carcinoma[J].Int J Mol Med,2004,14(3):389-395.
  • 5Fujimoto J,Toyoki H,Sato E,et al.Clinical implication of expression of vascular endothelial growth factor-C in metastatic lymph nodes of uterine cervical cancers[J].Br J Cancer,2004,91(3):466-469.
  • 6Ohta Y,Nozawa H,Tanaka Y,et al.Increased vascular endothelial growth factor and vascular endothelial growth factor-c and decreased nm23 expression associated with microdissemination in the lymphnodes in stage Ⅰ non-small cell lung cancer[J].J Thorac Cardiovasc Surg,2000,119(4Pt1):804-813.
  • 7胰腺癌诊治指南[J].中华外科杂志,2007,45(19):1297-1299. 被引量:13
  • 8Parkin DM,Bray F,Ferlay J,et al.Global cancer statistics,2002.CA Cancer J Clin,2005,55:74-108.
  • 9Jemal A,Siegel R,Xu J,et al.Cancer statistics,2010.CA Cancer J Clin,2010,60:277-300.
  • 10Baron TH,Kozarek RA.Preoperative biliary stents in pancreatic cancer proceed with caution.N Engl J Med,2010,362:170-172.

共引文献72

同被引文献49

  • 1张小博,李艳会,李开良,张平.VEGF、MMP-2、MMP-9在胰腺癌中的表达及临床意义[J].中国老年学杂志,2014,34(2):327-329. 被引量:16
  • 2Costello E, Greenhalf W, Neoptolemos JP. New biomarkers and targets in pancreatic cancer and their application to treatment [J]. Nat Rev Gastroenterol Hepatol, 2012, 9(8):435-444.
  • 3Gupta SC, Kismali G, Aggarwal BB. Curcumin, a component of turmeric: from farm to pharmacy[J].Biofactors, 2013, 39 (1) : 2-13.
  • 4Park W, Amin AR, Chen ZG, et al. New perspectives of curcumin in cancer prevention[ J]. Cancer Prevention Research, 2013, 6(5) : 387-400.
  • 5Beevers CS, Zhou H, Huang S. Hitting the golden TORget: curcumin's effects on roTOR signaling[ J]. Anti-cancer Agents Med Chem, 2013, 13(7) : 988-994.
  • 6Wu Q, Wang R, Yang Q, et al. Chemoresistance to gemcitabine in hepatoma cells induces epithelial-mesenchymal transition and involves activation of PDGF-D pathway[J]. Oncotarget, 2013,4 (11) : 1999-2009.
  • 7American Cancer Society. Cancer Facts & Figures 2015 [ M ]. Atlanta : American Cancer Society ;2015.
  • 8Scheffel DL, Hebling J, Scheffel RH, et al. Inactivation of matrix-bound matrix metalloproteinases by cross-linking agents in acid-etched dentin[J]. Oper Dent, 2014, 39(2): 152-158.
  • 9Wang WQ, Liu L, Xu HX, et al. Intratumoral SMA enhances the prognostic potency of CD34 associated with maintenance of microvessel integrity in hepatocellular carcinoma and pancreatic cancer[J]. PloS One, 2013, 8(8) : e71189.
  • 10田芳,柴玉荣,江亚南,张晓艳.姜黄素通过下调IκBα磷酸化抑制食管鳞癌细胞的体外增殖[J].基础医学与临床,2011,31(7):767-772. 被引量:12

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