摘要
槲皮素属于生物黄酮类,广泛分布于人们的食用植物中。槲皮素具有多方面的生物活性。槲皮素作为一个对人们健康非常有益的天然化合物,近几年来引起了国内外研究者的广泛的兴趣,研究论文呈直线上升趋势。自由基可导致细胞损伤,是产生许多疾病的主要原因。槲皮素主要的功能是抗氧化,清除自由基。槲皮素能使血管舒张作用,改善内皮细胞、加强氧化应激;抑制低密度脂蛋白氧化;减少粘附分子和其他炎症标记物;防止神经元氧化和炎性损伤血管内皮功能。槲皮素还可通过清除超氧阴离子、羟自由基及与自由基相关酶作用对抗氧化应激过程,从而保护心肌细胞。大量的证据表明,多食用含有槲皮素的水果和蔬菜可减少心血管疾病。槲皮素可以阻止潜在的致癌物成为最终的致癌物。研究表明槲皮素能有效地阻止环境中致癌物在人体内的活化;能加快致癌物在人体内的降解,并促进其排出;能诱导肿瘤细胞的分化,促进肿瘤细胞的凋亡。槲皮素对癌症防治具有重要作用。
Belonging to bio-flavonoids quercetin, are widely distributed in food plants. Quercetin has a wide range of biological activities. Quercetin as a natural compound that is very beneficial to people's health, attracted the interest of researchers widely at home and abroad in recent years, research paper on a rising trend. Free radicals can cause cell damage , was the main cause of many diseases. Quercetin main function is antioxidant, scavenging free radicals.Vasodilation effect of quercetin, improved, enhanced oxidative stress in endothelial cells; inhibit low density lipoprotein oxidation; reduce adhesion molecules and other inflammatory markers ; preventing neuronal oxidative and inflammatory injury of vascular endothelial function. Quercetin can also scavenge superoxide anion, hydroxyl free radical and enzyme effects against oxidative stress and free radical processes, thereby protecting myocardial cells. Abundant evidence showed that consumption of fruits and vegetables contain quercetin can reduce cardiovascular disease. Quercetin can prevent potential carcinogens into the ultimate carcinogen. Studies had shown that quercetin can effectively prevent the activation of carcinogens in the environment in the human body; can accelerate the degradation of carcinogen in humans, and promoting their discharge; can induce differentiation of tumor cells, promoting apoptosis of tumor cells. An important role of quercetin on cancer prevention and treatment.
出处
《食品研究与开发》
CAS
北大核心
2015年第7期118-122,共5页
Food Research and Development
基金
郑州大学大学生创新创业训练计划项目(2014xjxm315)
关键词
槲皮素
健康
抗癌
自由基
清除
quercetin
health
anticancer
free radical
scavenging