缩宫素不同应用方案在剖宫产患者中的效果评价

Comparison of the effects of different applications of oxytocin in cesarean patients

目的评价剖宫产术中缩宫素的最佳给药方案,分析降低剖宫产术并发症的发生原因。方法 600例自行选择剖宫产术的孕产妇随机分为子宫肌注射组(A组)、静滴组(B组)及缩宫素肌注+静滴组(C组),各200例。比较三组的产后出血发生率、胎盘自然剥离时间、术中及术后出血量,并比较三组不良反应发生情况。结果与A组和B组相比,C组胎盘自然剥离比率最高,且所需时间最短,术中及术后出血最少,产后出血发生率最低,差异具有统计学差异(P<0.05);缩宫素的不同用药方案对血压、心率等影响差别不大,不良反应发生率比较无统计学差异(P>0.05)。结论剖宫产患者在胎儿娩出后立即注射缩宫素10U,同时缩宫素10U加入林格氏注射液500ml静滴,有助于胎盘快速自然剥离,有效减少出血量,降低产后出血的发生率,效果确切,值得临床上推广。

Objective To analyze and compare the effects of oxytocin during cesarean section to find the best do- sing regimen and reduce the incidence of cesarean complications. Methods 600 cesarean patients were randomly divided into three groups. Group A was uterine muscle injection group. Group B was infusion group. Group C was intravenous oxytocin infusion ＋ intravenous group. The incidence of postpartum hemorrhage, the placenta naturally stripping time, intraoperative and postoperative bleeding, and adverse events were observed and compared, Results Compared with group A and group B, Placental natural stripping rate of Group C was the highest and its time was the shortest. Group C also had the lowest incidence of postpartum hemorrhage, the difference was statistically significant （P〈0.05）. Shrink different regimens of oxytocin in blood pressure, heart rate and other effects on very different. There was no statistically significant difference （P〉0. 05） of the incidence of adverse reactions. Conclusion After the baby is delivered, immedi- ately injection of oxytocin 10 U, 10 U of oxytocin while adding Ringer＇s Injection 500 ml infusion can help the placenta naturally fast stripping and effectively reduce the amount of bleeding and postpartum hemorrhage incidence.