老年住院患者慢性肾脏病及其相关危险因素分析

Chronic kidney disease and its related risk factors in elderly inpatients

目的探讨老年住院患者慢性肾脏病(chronic kidney disease,CKD)的临床特征及其相关危险因素。方法四川省人民医院老年科年龄60岁以上的老年住院患者603例,通过问卷调查及实验室检查搜集数据资料。结果 603例调查对象中,374例(62.02%)诊断为CKD,205例(34.00%)肾小球滤过率估计值(e GFR)<60 ml/(min·1.73m2)。CKD分期主要集中在CKD 3期,各年龄组间CKD构成差异有统计学意义(P<0.001)。317例(52.57%)出现白蛋白尿,不同年龄组间白蛋白尿情况比较差异无统计学意义(P>0.05)。多元Logostic回归分析结果提示:年龄、婚姻、饮酒、高血压、糖尿病、冠心病是CKD的独立危险因素。结论老年住院患者中CKD的发生率高,导致其发生的危险因素多。临床医生需对老年住院患者进行早期CKD的筛查,采取相应措施延缓CKD进展,减少其终点事件的发生,减轻社会及家庭的负担。

Objective To investigate the clinical characteristics of hospitalized elderly patients with chronic kidney disease （ CKD） and its related risk factors .Methods Data of questionnaire surveys and laboratory examinations were collected from 603 elderly inpatients over 60 years old at the department of elderly cadre health of Sichuan Provincial People ’s Hospital .Results Of the 603 pa-tients,374 cases（62.02%）were diagnosed as CKD,and 205 cases（34.0%）had glomerular filtration rate（eGFR）〈60 ml/（min-1.73 m2）.The most CKD patients were CKD3 stage and the constituent ratio of CKD in different age groups was significantly different （P〈0.001）.There were 317 cases（52.57%）with albuminuria,but no statistical difference in albuminuria was found among different age groups.Multivariate logostic regression analysis showed that age ,marriage,smoking,drinking,hypertension,diabetes and coronary heart disease were relative risk factors of CKD .Conclusion There is high incidence of CKD in hospitalized elderly patients .The relative risk factors of the disease were complex .Clinicians should perform an early screen for CKD in these patients ,take the corresponding meas-ures to delay the progression of the disease ,and reduce the cardiovascular events ,thus,reduce the burden on society and their families .