岭南传统天灸3号方治疗颈椎病颈痛的临床研究

Clinical study of No.3 prescription of traditional Tianjiu therapy of Lingnan for neck pain of cervical spondylosis

目的:评价岭南传统天灸3号方治疗颈椎病颈痛的临床疗效。方法:进行一项随机双盲安慰对照试验,将317例受试者随机分配到治疗组(109例)、对照组(108例)和安慰组(100例)。应用岭南传统天灸的干预方法,其中治疗组应用岭南传统天灸3号方,对照组应用天灸散,安慰组应用安慰剂,采用Northwick Park颈痛量表(NPQ)及软组织张力测量为评价指标进行评价。结果:3组患者经治疗后NPQ评分均有下降,其中治疗组和对照组下降幅度最大,安慰组稍有下降,干预前后NPQ评分比较差异有统计学意义(P<0.05),提示3种干预方案均可在一定程度上缓解颈痛情况,但治疗组和对照组疗效更为显著,且治疗组稍优于对照组。治疗结束时点,3组D0.5kg测量值均较治疗前升高,随访1个月时点,对照组与安慰组均较治疗结束时下降,而随访3个月时则3组均有下降,且干预前后评分比较差异有统计学意义(P=0.000);而S测量值上,干预后和随访期治疗组与对照组均较治疗前升高,而安慰组则基本平稳,且干预前后比较差异有统计学意义(P<0.05)。结论:岭南传统天灸3号方可以加强对项痹的疗效,值得推广应用。

Objective： To assess the clinical efficacy of No. 3 prescription of traditional Tianjiu therapy of Lingnan in treating neck pain. Methods： A double blind, randomized controlled trial was conducted, in which 317 patients were recruited and randomly allocated to the treatment group （109 patients）, control group （108 patients） and sham group （100 patients）. Traditional Tianjiu therapy of Lingnan was used as intervention method, the treatment group used No. 3 prescription of traditional Tianjiu therapy of Lingnan, the control group used Tian-jiu powder, and the sham group used placebo. NPQ scale and tension of soft tissue test were used as the outcomes. Results： Analysis showed that NPQ scores of three groups were decreased, the treatment group and control group decreased more than sham group, differences of scores before and after treatment were significant （P〈0.05）, which indicated all three treatment could release neck pain in some extend, and treatment and control group were better. After treatment, D05kg tests of tension of soft tissue in three groups were all increased than before treatment. But in the 1-month- follow-up time point, D05kg tests of control group and sham group were decreased than before, and in the 3-month-follow-up time point, D05kg tests of all three groups were decreased than before. Analysis showed that all differences of scores before and after treatment were significant （P=0.000）. On tests of S scores of tension of soft tissue, all scores of treatment group and control group were increased than before treatment, while sham group was keeping stable, and the differences among groups were significant （P〈0.05）. Conclusion： The clinical efficacy of No. 3 prescription of traditional Tianjiu therapy of Lingnan for neck pain of cervical spondylosis could be enhanced than the original prescription, and it＇s worthy to be spread.