摘要
目的:研究杜鹃兰假鳞茎的化学成分。方法:利用正相硅胶柱色谱、Sephadex LH-20、反相制备液相色谱等方法进行分离纯化,并通过1H-NMR、13C-NMR等波谱技术进行结构鉴定。结果:从杜鹃兰假鳞茎的乙酸乙酯部位中分离得到10个化合物,分别鉴定为:shancigusinⅠ(Ⅰ)、4-O-β-D-glucopyranosyl cinnamate(Ⅱ)、bulbocodin D(Ⅲ)、blestriarene A(Ⅳ)、7-羟基-2,4-二甲氧基菲(Ⅴ)、coelonin(Ⅵ)、militarine(Ⅶ)、天麻苷(Ⅷ)、3-羟基苯丙酸(Ⅸ)、肉桂酸(Ⅹ)。结论:其中,化合物Ⅰ~Ⅲ、Ⅸ、Ⅹ为首次从该植物中分离得到。
Objective : To study the chemical constituents of Cremastra appendiculata. Methods : The compounds were isolated by re- peated column chromatography with silica gel, Sephadex LH-20 and ODS-HPLC. The structures were elucidated by analysis of spectro- scopic data(1H-NMR and 13 C-NMR). Results:Ten compounds were isolated from the EtOAe extract in the tuber of Cremastra appendic- ulata. Their structures were identified as shancigusin Ⅰ ( Ⅰ ) ,4-O-β-D-glucopyranosyl cinnamate(Ⅱ) ,bulbocodin D( Ⅲ ) ,blestriarene A( Ⅳ ) ,7-hydroxy-2,4-dimethoxy phenanthrene( Ⅴ ), coelonin (Ⅵ ), militarine ( Ⅶ ), gastrodine ( Ⅷ ), 3-hydroxyphenylpropionie acid (Ⅸ) and cinnamic acid( Ⅹ ). Conclusion:Compounds Ⅰ - Ⅲ, Ⅸ and Ⅹ are isolated from Cremastra appendiculata for the first time.
出处
《中药材》
CAS
CSCD
北大核心
2015年第2期298-301,共4页
Journal of Chinese Medicinal Materials
基金
国家青年自然科学基金(31100261)
关键词
杜鹃兰假鳞茎
化学成分
二苯乙烯类化合物
酚类化合物
Cremastra appendiculata ( D. Don) Makino
Chemical constituents
Stilbenoids
Phenolic compounds