杜仲腰痛丸治疗慢性腰痛的临床随机对照研究

The Randomized Control Research of DuZhong YaoTong Pill on Chronic Lumbago

目的:观察杜仲腰痛丸治疗慢性腰痛和预防复发的临床疗效。方法:将98例慢性腰痛患者,按照1∶1比例完全随机分为2组。对照组49例给予常规治疗;观察组49例给予常规治疗联合杜仲腰痛丸治疗,2组均连续治疗4周。所有患者分别于治疗前、治疗后1个月、3个月、6个月统计疼痛视觉模拟评分(VAS)、Oswstry功能障碍指数(CODI)值,随访复发情况。结果:2组治疗后VAS、CODI评分较治疗前均明显降低(P<0.05);组内比较,对照组治疗3个月、6个月VAS、CODI评分比较,差异无统计学意义(P>0.05),观察组在不同时间比较,差异均无统计学意义(P<0.05);组间比较,2组在治疗1个月VAS、CODI评分比较,差异无统计学意义(P>0.05),而治疗3个月、6个月比较差异有统计学意义(P<0.05)。观察组的复发率低于对照组(P<0.05)。结论:杜仲腰痛丸能增强慢性腰痛的长期治疗效果,包括减轻疼痛症状,改善腰部功能活动,并能预防慢性腰痛的复发。

To observe the clinical efficacy ofDuZhongYaoTongpill in treating chronic lumbago and preventing relapse. Methods： Totally 98 patients with chronic lumbago were randomly assigned to two groups on average. 49 cases in the control group were treated with routine therapy for four weeks continuously, as well as the observation group undergoing routine therapy andDuZhongYaoTongpill. VAS and CODI of all the cases were evaluated respectively before treatment and at the end of 1st, 3rd and 6th month with follow-up of relapse. Results： The scores of VAS and CODI decreased significantly after treatment （P〈0.05） in both groups. The comparison of these scores in the control group showed that the difference before and after treatment at 3rd and 6th month had no statistical meaning（P〈0.05）, so did the observation group in each times（P〈0.05）. In the comparison of scores in 1st month between two groups had no statistical meaning, while there was statistical meaning at 3rd and 6th month. The recurrence rate of the observation group turned out to be lower than that of the control group. Conclusion：DuZhong YaoTongpill could enhance the therapeutic effect of chronic lumbago, which includes relieving pain of patients, improving the functional activity of the waist and preventing the relapse of chronic lumbago.