血栓通联合胞二磷胆碱治疗急性脑梗塞60例

Treatment for 60 Cases of Acute Cerebral Infarction by XueShuanTong Combined with Citicoline

目的:观察注射用血栓通联合胞二磷胆碱治疗急性脑梗塞的临床疗效。方法:将120例急性脑梗塞患者随机分为2组,治疗组60例,给予注射用血栓通500 mg加入0.9%氯化钠注射液250 m L,胞二磷胆碱0.75 g加入5%葡萄糖注射液250 m L,静脉滴注,1次/d,疗程14天;对照组60例,给予胞二磷胆碱0.75 g加入5%葡萄糖注射液250 m L,静脉滴注,1次/d,疗程14天。比较治疗前、后症状改善及神经功能缺损评分情况。结果:总有效率治疗组为96.00%,对照组为80.00%,2组比较差异有统计学意义(P<0.05)。神经功能缺损评分治疗组改善较对照组明显(P<0.05)。结论:注射用血栓通联合胞二磷胆碱注射液治疗急性脑梗死临床疗效显著。

To observe clinical efficacy ofXueShuanTonginjection combined with citicoline in the treatment of acute cerebral infarction. Methods： Totally 120 patients with acute cerebral infarction were randomly divided into the treatment group and the control group. 60 cases in the treatment group were givenXueShuanTong injection, 500 mg, plus 250 mL 0.9% sodium chloride injection, and 0.75 g citicoline plus 250 mL 5% glucose injection, via intravenous injection （IV）, once per day, for 14 days; 60 cases in the control group were given 0.75g citicol-ine plus 250 mL 5% glucose injection, via IV, once per day, for 14 days. The improvements of symptoms and neuro-logical severity score were compared before and after the treatment. Results： Total effective rate was 96.00% in the treatment group, and 80.00% in the control group, indicating a significant difference between two groups （P〈0.05）. The improvement of neurological severity score in the treatment group was more significant compared with that in the control group （P〈0.05）. Conclusion： The clinical efficacy ofXueShuanTonginjection combined with citicoline is significant in the treatment of acute cerebral infarction.