柴胡地骨皮汤联合复方氯已定含漱液治疗复发性口腔溃疡的临床观察

The Curative Effect of Chaihudigupitang and Compound Chlorhexidine Gargle on Recurrent Oral Ulcer

目的观察柴胡地骨皮汤联合复方氯已定含漱液治疗复发性口腔溃疡的疗效。方法将98例复发性口腔溃疡患者随机分为治疗组49例和对照组49例,对照组口服维生素C及维生素B2,并使用复方氯已定含漱液含漱,治疗组在对照组的基础上,服用柴胡地骨皮汤,进行12-18个月的临床观察。结果两组患者相比,近期疗效和远期疗效均有显著性差异（P〈0.05）,治疗组总有效率显著高于对照组（P〈0.05）。结论柴胡地骨皮汤合并复方氯已定含漱液治疗复发性口腔溃疡安全,疗效显著,具有推广价值。

Objective To observe the curative effect of Chaihudigupitang and Compound Chlorhexidine Gargle on recurrent oral ulcer. Methods 98 patients diagnosed as recurrent oral ulcer were divided into two groups, the treatment group （49 cases） and the control group （49 cases）. The patients of control group take vitamin C and vitamin B2 orally, and were treated with Compotmd Chlorhexidine Gargle at the same times. The patients of treatment group take vitamin C, vitamin B2 and Chaihudigupitang orally, and were treated with Compound Chlorhexidine Gargle at the same times. The curative effects were observed for about 12 - 18 m. Results Significent differents of the recent curative effect and the forward curative effect between the two groups were obversed （P 〈 0.05）. The total effective rate in treatment group is significantly higher than the control group （P 〈 0.05）. Conclusion It may be safe and effective for Chaihudigupitang and Compound Chlorhexidine Gargle to be used together in curing the recurrent oral ulcer.