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肠道微生态与肠黏膜免疫 被引量:3

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摘要 胃肠道是机体接触外界抗原物质最广泛的部位,也是人体中最大、最复杂的微生物储存库,但胃肠黏膜为什么能够选择性地允许肠腔内容物中的营养成分、药物等进入而阻止细菌及毒素等抗原进入呢?这除了胃肠黏膜屏障外,还与肠黏膜免疫密切相关.人生只有一个阶段和微生物绝缘,即子宫内的胎儿,胎儿因此没有肠黏膜免疫,反之,胎儿将面临流产的厄运.出生后,在肠道微生物的训练下,肠黏膜免疫逐渐发育成熟,成为机体与微生物和谐相处一生的重要生理功能.
出处 《中华内科杂志》 CAS CSCD 北大核心 2015年第5期405-407,共3页 Chinese Journal of Internal Medicine
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