韦格纳肉芽肿所致喉气管狭窄的诊断及治疗

Laryngeal and tracheal stenosis caused by Wegener′s granulomatosis

喉气管狭窄是临床上棘手的问题,引起喉气管狭窄的病因有很多,如外伤、喉结核、恶性肿瘤、手术损伤、长期带气管套管等,其中一部分喉气管狭窄与韦格纳肉芽肿病有关,临床上表现为进行性呼吸困难、喘鸣,必要时需紧急行气管切开。韦格纳肉芽肿病又称为肉芽肿性血管炎,属于一种自身免疫性疾病,主要累及中小动静脉、毛细血管,偶尔累及大动脉。

Summary Wegener＇s granulomatosis （WG） is a multisystem disease characterized by necrotizing granulomatous inflammation and vasculitis. WG classically involves the upper airway, lung and kidneys. Otolaryngologic manifestations are often the presenting symptoms in WG, Subglottic stenosis is a less common, but a lifethreatening manifestation of WG, This paper studies about the laryngeal and tracheal stenosis diagnosis and surgical treatment of Wegener＇s granulomatosis in the past 20 years.