复方消化酶并双歧三联活菌对围手术期病人术后胃肠功能异常影响

THE EFFECT OF PERIOPERATIVE APPLICATION OF COMPOUND DIGESTIVE ENZYME PLUS BIFID TIPLE VIABLE ON POSTOPERATIVE GASTROINTESTINAL DYSFUNCTION

目的了解围手术期联合应用复方消化酶和双歧三联活菌对术后胃肠功能异常的预防及改善效果。方法选择手术病人400例,根据围手术期用药不同分为联合用药组（联合应用复方消化酶和双歧三联活菌）、活菌组（仅应用双歧三联活菌）、消化酶组（仅应用复方消化酶）和对照组（不应用复方消化酶和双歧三联活菌）,各100例,分别对4组病人术后首次排气、排便的时间以及出现恶心、纳差、腹胀、腹痛的程度进行观察和比较。结果联合用药组首次排气、排便时间与其他3组比较,差异有显著性（F=4.27~66.00,P〈0.05）。联合用药组除腹痛评分与消化酶组和活菌组比较差异无显著性外,其余指标评分与各组比较,差异均有显著性（F=5.32~58.50,P〈0.05）。结论围手术期联合应用复方消化酶和双歧三联活菌能够有效预防和改善术后胃肠功能异常。

Objective To understand the effects of perioperative medication of compound digestive enzyme and bifid tiple viable on gastrointestinal dysfunction after surgery. Methods According to different medications during perioperative period, 400 patients who underwent surgery were selected and evenly divided into four groups as combination group （oral compound diges- tive enzyme and bifid triple viable were offered; viable organism group） oral bifid triple viable only; digestive enzyme group-oral compound digestive enzyme only; and control group-neither of compound digestive enzyme and bifid triple viable was given. The time of first aerofluxus and defecation, and nausea, poor appetite, abdominal distension and abdominal pain were observed and compared among the four groups. Results The differences of time of the first aerof｜uxus and defecation between the combination group and the other three groups were significant F= 4.27- 66.00, P〈0.05）. The differences between combination group and both viable organism group and digestive enzyme group were not significant with regard to the score of abdominal pain, and the differences of the other items mong them were significant （F= 5.32- 58.50, P 〈0.05）. Conclusion Combination use of oral compound digestive enzyme and bifid tiple viable can effectively prevent and improve postperative gastrointestinal dysfunction.