丝涤混构小口径人造血管的结构与性能

Structure and Properties of the Silk-Polyester Interwoven Small-Diameter Vascular Prosthesis

为了获得力学性能及生物学性能俱佳的小口径人造血管,设计并制备出一系列丝涤混构的机织小口径人造血管管坯,并对其进行结构表征及力学性能研究.结果表明:纱线线密度与组织类型决定人造血管中丝素的表达率与分布;所有试样的径向拉伸强度均优于商用人造血管;顶破强度不低于商用ePTFE人造血管(SW),且均优于犬股动脉;水渗透性值均低于170mL/(cm2·min),移植前无需预凝;所有试样的顺应性均优于对照样SW.

In order to obtain small-diameter vascular prosthesis with excellent mechanical properties and biocompatibility, a series of silk-polyester interwoven small-diameter vascular prostheses were designed and fabricated, in addition, their structure and mechanical properties were evaluated. The silk expression rate and distribution depended upon the yarn linear density and fabric structure. Overall, the radial strength of all the samples were superior to that of the commercial sample, the bursting strength of all the samples were no worse than that of SW, even better than that of the canine femoral artery. The water permeability of all the samplcs was lower than 170 mL/（cm2 ~ min）, which made the samples preclot-free. The compliance of all the samples was superior than that of SW.