超声对胎儿丘脑、尾状核和豆状核的测量在产前诊断中的意义

Ultrasonic measurements of fetal thalamus, caudate nucleus and lenticniar nucleus in prenatal diagnosis

目的通过胎儿丘脑横切面测量胎儿丘脑长径、横径，尾状核长径、横径和豆状核长径、横径，建立胎儿丘脑、尾状核和豆状核径线随孕周变化的参考值范围。方法随机选取2012年11月至2014年8月于吉林大学第二医院妇产科就诊孕妇265例，取胎儿丘脑横切面测量胎儿丘脑长径、横径，尾状核长径、横径和豆状核长径、横径，采用SPSS19．0统计软件，计算出胎儿上述径线随孕周变化的回归曲线，以P〈0．05为差异有统计学意义。结果胎儿丘脑长径和孕周的线性回归方程为：Y=0．051X＋0．201，R=0．876，胎儿丘脑横径和孕周的线性回归方程为：Y=0．031X＋0．229，R=0．817，胎儿尾状核头长径和孕周的线性回归方程为：Y=0．033X＋0．101，R：0．722，胎儿尾状核头横径和孕周的线性回归方程为：R=0．025—0．046，R=0．711，胎儿豆状核长径和孕周的线性回归方程为：Y=0．046＋0．229，R=0．765，胎儿豆状核横径和孕周的线性回归方程为：Y=0．025—0．05，R=0．772。结论胎儿丘脑横切面测量各径线随胎儿孕周增加而增大，并和孕周呈线性回归关系。

Objective To establish the reference values of thalamus, caudate nucleus and lenticular nucleus diameters through fetal thalamic transverse section. Methods A total of 265 fetuses at our hospital were randomly selected from November 2012 to August 2014. And the transverse and length diameters of thalamus, caudate nucleus and lenticular nucleus were measured. SPSS 19.0 statistical software was used to calculate the regression curve of fetal diameter changes and gestational weeks of pregnancy. P 〈 0.05 was considered as having statistical significance. Results The linear regression equation of fetal thalamic length diameter and gestational week was ： Y = 0.051X ＋ 0. 201, R = 0. 876, linear regression equation of thalamic transverse diameter and fetal gestational week was： Y = 0. 031X ＋ 0. 229, R = 0. 817, linear regression equation of fetal head of caudate nucleus length diameter and gestational age was： Y = 0.033X ＋ 0. 101, R = 0. 722, linear regression equation of fetal head of caudate nucleus transverse diameter and gestational week was： R = 0. 025 -0. 046, R = 0. 711, linear regression equation of fetal lentiform nucleus length diameter and gestational week was ： Y = 0. 046 ＋ 0. 229, R = 0. 765, linear regression equation of fetal lentiform nucleus diameter and gestational week was ： Y = 0. 025 - 0.05, R = 0. 772. Conclusions Ultrasonic measurement of diameter of fetal thalamus caudate nucleus, and lenticular nucleus through thalamic transverse section is simple and convenient. And measurements increase with fetal gestational weeks and there is linear regression relationship between them.