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间充质干细胞旁分泌机制在ARDS治疗中的研究进展 被引量:7

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摘要 急性呼吸窘迫综合征(ARDS)是危重症患者死亡的一个主要原因之一。尽管随着对ARDS的研究的深入和临床治疗措施的不断进步,其病死率较前有所下降,但研究显示,目前ARDS的病死率仍高达40%。然而,临床对于ARDS的治疗仍停留在机械通气和限制补液等支持治疗的层面上,至今为止尚无有效的药物治疗措施。间充质干细胞(MSC)具有多向分化潜能,在移行至肺损伤部位后能分化为肺泡上皮细胞和肺微血管内皮细胞,从而修复损伤肺组织结构,保护肺功能。
出处 《中华医学杂志》 CAS CSCD 北大核心 2015年第19期1544-1546,共3页 National Medical Journal of China
基金 国家自然科学基金(81170057,81300060),江苏省自然科学基金(BK20131302)
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