He-Ne激光照射联合湿润烧伤膏治疗外阴溃疡32例的临床疗效观察

Clinical observation of He-Ne laser irradiation combined with Moist Exposed Burn Ointment in treatment of 32 cases with ulcus vulvae

目的探讨He-Ne激光照射联合湿润烧伤膏治疗外阴溃疡的临床治疗效果。方法选择2012年6月-2014年5月期间我科门诊收治的64例外阴溃疡患者,随机分为观察组和对照组两组,观察组给予He-Ne激光联合湿润烧伤膏进行治疗,对照组予以单纯He-Ne激光照射治疗,观察比较两组临床疗效。结果观察组临床治疗总有效率为100.00%,对照组临床治疗总有效率为90.63%,两组总有效率比较差异有统计学意义(P<0.05);观察组症状缓解、皮损好转及溃疡愈合时间分别为(2.01±0.68)d、(3.16±2.04)d、(5.33±1.86)d,与对照组(3.05±0.93)d、(5.86±2.51)d、(8.83±2.64)d比较,差异均有统计学意义(P<0.001)。结论 He-Ne激光照射联合湿润烧伤膏治疗外阴溃疡临床疗效显著,且可大大缩短疗程,值得临床推广应用。

Objective To discuss the clinical efficacy of He-Ne laser irradiation combined with Moist Ex-posed Burn Ointment （MEBO）in treatment of ulcus vulvae. Methods Sixty-four cases with ulcus vulvae were included into the study cared at our outpatient department.According to the different treatment from June 2012 to May 2014,64 cases were randomly divided into an observation group and a control group.The ob-servation groups were given He-Ne laser combined with MEBO,and the control group only used He-Ne la-ser irradiation.The clinical efficacy was compared in two groups. Results The clinical total effective rate of observation group was 100.00%,significantly higher than that of the control group’s 90.63%,the difference was statistically significant （P 〈0.05）.The time of remission,lesions improved and ulcer healing for the ob-servation group were （2.01 ±0.68）days,（3.1 6 ± 2.04）days and （5.33 ± 1.86 ）days,and for the control group they were （3.05±0.93）days,（5.86±2.5 1）days and （8.83±2.64）days,respectively,group-paired comparison yielded statistically significant differences （P 〈 0.001 ）. Conclusion He- Ne laser irradiation combined with Moist Exposed Burn Ointment in treatment of patients with ulcus vulvae have significant effica-cy and can obviously shorten the time of treatment,it is worth recommendation in clinical.