中药联合抗真菌药物治疗真菌性角膜炎53例

Traditional Chinese Medicine Combined with Antifungal Agents for Treating Fungal Keratitis in 53 Cases

目的观察中药联合抗真菌药物治疗真菌性角膜炎的临床疗效。方法选取医院诊治的真菌性角膜炎患者106例,按就诊先后顺序将其分为试验组和对照组,各53例。对照组患者采用5%那他霉素滴眼液和0.2%氟康唑滴眼液滴眼治疗,试验组患者在对照组基础上采用玉屏风散合银花土茯苓汤内服和中药熏蒸患眼治疗。治疗15 d后进行疗效、视力、不良反应、痊愈时间等评估。结果试验组的疗效、视力和痊愈时间均明显优于对照组(P<0.05),两组患者不良反应发生情况无显著性差异。结论中西医结合治疗真菌性角膜炎可取得较好疗效,能缩短痊愈时间,值得临床推广。

Objective To observe the clinical effect of traditional Chinese medicine combined with antifungal agents in treating fungal keratitis. Methods Totally 106 patients with fungal keratitis in the hospital were selected and divided into the experimental group and the control group,53 cases each. The control group adopted 5% Natamycin Eye Drops and 0. 2% Fluconazole Eye Drops for treatment, while on this basis the experimental group adopted oral Yupingfeng Powder and Yinhuatufuling Decoction,and traditional Chinese medicine fumigation eye treatment. The curative effect,vision,adverse reactions and cure time after 15 d treatment were evaluat-ed. Results The experimental group was significantly better than the control group in the curative effect,visual acuity and cure time （ P ﹤ 0. 05）;the adverse reactions had no statistically significant difference between the two groups. Conclusion The integrated tradi-tional Chinese and Western medicine for treating fungal keratitis can obtain better curative effect,shorten the cure time and deserves to be promoted in clinic.