胃肠道神经内分泌肿瘤的诊断和治疗进展

Progress of the diagnosis and treatment of gastrointestinal neuroendocrine tumors

胃肠道神经内分泌肿瘤（GI-NET）是起源于消化道肽能神经元和神经内分泌细胞的一类肿瘤，能产生肽类激素，引起类癌综合征，但临床上出现典型症状者较少见。由于诊断技术及对该病认识的进步，发病率有所上升。目前治疗措施是以手术切除为主，联合化疗、靶向治疗的综合疗法。

Gastrointestinal neuroendocrine tumor（GI-NET）originates from peptide neurons and neu-roendocrine cells in gastrointestinal tract,and secrets peptide hormones,leading to carcinoid syndrome which rarely happens in clinical practice. Because of the improvement of diagnostic method and understanding of this rare disease,the morbidity is rising in recent years. The main treatments of GI-NET are surgery and compre-hensive therapy,consisting of chemotherapy and targeted therapy.