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姜黄素对类风湿关节炎骨破坏的影响机制 被引量:3

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摘要 破骨细胞作为唯一的骨吸收细胞,在类风湿关节炎(RA)骨破坏过程中发挥关键性作用。姜黄素通过抑制对破骨细胞生成具有正调节作用的细胞因子如RANKL和TNF-α等、细胞内信号通路的调节和相关蛋白酶的影响,来阻断RA的骨破坏进程。因此姜黄素可能成为治疗RA骨破坏的重要物质。
出处 《现代医学》 2015年第4期531-535,共5页 Modern Medical Journal
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