玻璃体后脱离与糖尿病视网膜病变

Posterior vitreous detachment and diabetic retinopathy

玻璃体后脱离（posterior vitreous detachment,PVD）在糖尿病视网膜病变（diabetic retinopathy,DR）的发展过程、手术治疗和转归等方面发挥了重要作用.部分PVD可以加重DR的病情,完全PVD可以消除新生血管生长支架,减少玻璃体出血,增加氧气浓度,使玻璃体手术简单化等.副作用小的纤溶酶等药物玻璃体内注射可以诱导PVD,其可改变DR的转归和减少玻璃体手术并发症.

Posterior vitreous detachment （PVD） in diabetic retinopathy （DR） has played an important role in the development process,and outcome of surgical treatment.Partial PVD can contribute to the worsening of DR.Neovascularization on the retinal surface cannot occur without an appropriate scaffold of collagenous material,complete PVD can eliminate the scaffold,reduce vitreous hemorrhage,increase vitreal oxygen levels,make surgery easier and safer.Intravitreal injection of plasmin and other drugs with little side effects can induce PVD,improve the surgical outcome of DR and reduce surgical complications.