摘要
Dear Editor,Large numbers of individuals experience low back pain(LBP)during their lifetime[1,2].LBP excruciates approximately 80%aging population and causes significant socio-economic problem[3,4].LBP often originates from the intervertebral disc degeneration(IVDD).The intervertebral disc(IVD)is a specialized biomechanical complex composed of a hyper-hydrated and oligocellular central structure,
Large numbers of individuals experience low back pail （LBP） during their lifetime . LBP excruciates approxi mately 80% aging population and causes significant so cio-economic problem . LBP often originates from the intervertebral disc degeneration （IVDD）. The intervertebra disc （IVD） is a specialized biomechanical complex com posed of a hyper-hydrated and oligocellular central structure namely, the nucleus pulposus （NP）, and the annulus fibrou： （AF） .
基金
supported by the National Natural Science Foundation of China(31172078)
Shanxi Province Science Foundation(2013011056-1)
