摘要
目的:观察舒郁合剂对抑郁症肝郁脾虚型患者血清五羟色胺(5-HT)含量的影响。方法:将100例抑郁症患者,随机分为治疗组和对照组各50例,治疗组服用舒郁合剂,对照组服用盐酸氟西汀胶囊,对两组患者治疗前后进行汉密尔顿抑郁量表(HAMD)评定、血清5-HT含量变化进行比较。结果:治疗8周后两组患者血清5-HT含量较治疗前均升高,差异有统计学意义(P<0.05);治疗后治疗组5-HT含量略高于对照组,但差异无统计学意义(P>0.05)。结论:舒郁合剂能够提高抑郁症患者血清5-HT的含量。
Objective: To observe the effects of Shuyu Mixture on the serum level of serotonin( 5-HT) in depressed patient with liver stagnation and spleen deficiency syndrome. Methods: 100 patients suffered from depression were divided into two groups randomly; 50 patients in treatment group were given Shuyu Mixture,the other 50 patients in control group were given fluoxetine hydrochloride. The serum level of serotonin( 5-HT) was determined and the Hamilton depression scale( HAMD) was used to compare the depression level. Results:After eight weeks of treatment,the serum level of serotonin( 5-HT) of patients in both groups increased with statistical significance. After treatment,the serum level of serotonin( 5-HT) in the treatment group was slightly higher than the patients in control group,but the difference has no statistical significance( P〈0. 05). Conclusion: Shuyu mixture can increase the serotine( 5-HT) level to a similar extent as fluoxetine hydrochloride after8 weeks of treatment.
出处
《贵阳中医学院学报》
2015年第3期36-38,12,共4页
Journal of Guiyang University of Chinese Medicine
基金
贵州省科学技术基金项目
项目合同编号:黔科合J字[2010]2222号