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Tau蛋白在多发性硬化中研究新进展 被引量:2

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摘要 多发性硬化(MS)是中枢神经系统(CNS)炎性脱髓鞘疾病,病因和发病机制尚不明确,其病理特点为不同程度髓鞘脱失、炎性细胞浸润、星形胶质细胞增生和轴索损伤。近年通过建立实验性变态反应性脑脊髓炎小鼠模型(EAE)来研究Tau蛋白与神经元及轴索损伤相关性[1],并且以Tau蛋白为治疗靶点的药物研究逐渐成为研究热点。
出处 《中国药物与临床》 CAS 2015年第5期650-651,共2页 Chinese Remedies & Clinics
基金 山西省自然科学基金(2013011052-3)
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