双氧水-氢溴酸光化学氧化合成1,3-二氯丙酮的研究

Photochemical Oxidation of 1,3-Dichloroacetone Using Hydrogen Peroxide/Hydrobromic Acid

目的优化1,3-二氯丙酮的合成工艺。方法和结果通过优化反应条件,调整并确定了原料比1,3-二氯丙醇:氢溴酸(HBr):双氧水=2:1:1.1。结论与文献方法相比,原料价廉易得且安全性提高,有较高的经济效益,且避免了铬污染的问题。

1,3-Dichloroacetone was synthesized from 1,3-Dichloro-2-propanol by the method of Photochemical oxidation using Hydrogen peroxide/hydrobromic acid. Through optimizing the reactive conditions, the mole ratio of 1, 3-Dichloro-2-propanol to hydrobromic acid to Hydrogen peroxide was determined as 2：1： 1.1. Compared with other method in the literature,the new process has advantage of decreasing material cost, improving security, simplifying operation and it is also an effective method to eliminate pollution.