奥拉西坦联合尼莫地平治疗血管性痴呆临床观察

Clinical Observation of Treatment of Vascular Dementia with Oxiracetam and Nimodipine

目的探析奥拉西坦联合尼莫地平治疗血管性痴呆的临床效果。方法将血管性痴呆患者100例作为研究对象,按入院先后顺序分为2组,其中给予对照组常规治疗,观察组则给予奥拉西坦和尼莫地平联合治疗,对比分析2组治疗效果。结果观察组30例临床控制,10例显效,7例有效,3例无效,治疗总有效率为94%;对照组15例临床控制,12例显效,13例有效,10例无效,治疗总有效率为80%。组间比较差异明显,具有统计学意义。结论临床上运用奥拉西坦和尼莫地平联合治疗血管性痴呆,不仅可以很好地控制病情,降低不良反应发生率,还能提高治疗效果,有效改善患者预后生活质量。

Objective To analyze treatment of vascular dementia with oxiracetam and nimodipine. Methods P100 patients with vascular dementia, as research subjects, divided into two groups according to the order of admission, were which conventional treatment administered to the control group, while the observation group were treated with oxi racetam and nimodipine treatment, comparative analysis of two therapeutic effect was carried out. Results The clinical control group of 30 patients, 10 cases were cured, 7 cases effective, 3 cases ineffective, the total effective rate was 94%; and 15 cases of controlled clinical control group, 12 cases were cured, 13 cases effective, 10 cases of ineffective treatment The total effective rate was 80%, significant differences between the two groups, with statistical significance （P 〈0.05）. Conclusion The use of nimodipine oxiracetam and combination therapy on the clinical vascular dementia, not only can well control the disease and reduce the incidence of adverse reactions, but also can improve the therapeutic effect, and effectively improve the quality of life of patients prognosis.