输尿管部分切除与全长切除在输尿管癌患者中的疗效对比

The Comparison of Partial Ureterectomy and Complete Ureterectomy in Patients with Ureteral Carcinoma

目的:对比输尿管部分切除与全长切除在输尿管癌治疗中的临床效果。方法:将68例原发性输尿管癌患者随机分为观察组(n=34)与对照组(n=34),观察组给予输尿管部分切除术治疗,对照组给予输尿管全长切除术(输尿管癌根治术)治疗,对比两组患者临床效果及术后生活质量。结果:两组患者术后1年膀胱癌发生率、肿瘤特异性生存率以及肿瘤相关死亡率比较差异均无统计学意义(P>0.05)。两组患者术后1年PF、GH、BP、RP、MH、VT、RE、SF八个维度的生存质量评分以及QOL总分比较差异均无统计学意义(P>0.05)。结论:对于早期、分级较低的肿瘤,若能够获得密切随访,可采用输尿管部分切除术治疗,且并不会增加术后膀胱癌发生率以及肿瘤相关死亡率。

Objective：To contrast the clinical effects of partial ureterectomy and complete ureterectomy in patients with ureteral carcinoma. Method：68 patients with ureteral carcinoma were randomly divided into the observation group（n=34）and the control group（n=34）,the observation group were treated with partial ureterectomy,the control group were treated with complete ureterectomy（radical resection of ureteral carcinoma）,then the clinical effects and the postoperative quality of life（QOL）were contrasted between the two groups. Result：There was no significantly difference in the incidence of bladder cancer,cancer specific survival,tumor related mortality after 1 years of the two groups （P〉0.05）;and no significantly difference in score of PF,GH,BP,RP,MH,VT,RE,SF,and total score of QOL after 1 years of the two groups（P〉0.05）. Conclusion：If the patients with early,lower grading ureteral carcinoma can get close follow-up,partial ureterectomy can be performed,it doesn’t increase the incidence of postoperative bladder cancer and tumor related mortality.