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亚砷酸为主方案治疗急性早幼粒细胞白血病的疗效及其随访研究 被引量:1

The Curative Effect of Using Arsenous Acid in Acute Promyelocytic Leukemia
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摘要 目的亚砷酸为主方案治疗急性早幼粒细胞白血病的临床效果。方法选择初诊患者125例分为亚砷酸+高三尖杉酯碱组、单独亚砷酸组、亚砷酸+其它化疗药物组,进行比较。结果前组较后两组完全缓解率比较,差异有统计学意义(P<0.05)。前组较后两组生存率比较差异有统计学意义(P<0.05)。结论亚砷酸与高三尖杉酯碱联合诱导方案能够显著提高初诊急性早幼粒细胞白血病完全缓解率。 Objective To study the arsenic acid as the main solution for use in acute promyelocytic leukemia clinical effect.Methods Divided 26 patients into arsenous acid + three pointed cedar ester base group, the separate arsenite group, arsenic acid + other chemotherapy drugs group.Results The former group than in the two groups after complete remission rate comparison, the difference was statistically significant (P〈0.05). Before the group later survival compared the two groups was statistically signiifcant difference (P〈0.05).Conclusion Arsenous acid with Homobarringtonie base joint induction programme can improve both the acute myelocytic leukemia complete response rate signiifcantly.
出处 《中国继续医学教育》 2015年第12期129-130,共2页 China Continuing Medical Education
关键词 亚砷酸 高三尖杉酯碱 急性早幼粒细胞白血病 Arsenous acid Homobarringtonie Cub early acute myeloid leukemia
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  • 1张欣,张春梅,孙兆刚,滕清良,李秀兰,黎爱华.全反式维甲酸、三氧化二砷治疗急性早幼粒细胞白血病疗效分析[J].社区医学杂志,2005,3(7):13-14. 被引量:2
  • 2Wang ZY,Chen Z.Acute promyelocytic leukemia:from highly fatal tohighly curable[J]. Blood,2008,111(5):2505-2515.
  • 3Sakoe Y,Sakoe K, Kirito K, et al.F0X03A as a key molecule forall -trans retinoic acid -induced granulocytic differentiation andapoptosis in acute promyelocytic leukemia [J].Blood,2010,115(18):3787-3795.
  • 4Zhou J, Zhang YM, Li JM, et al. Single-agent arsenic trioxide inthe treatment of children with newly diagnosed acute promyelocyticleukemia[J].Blood,2010,115(9):1697-1702.
  • 5O'Connell PA, Madureira PA, Berman JN, et al. Regulation ofS100A10 by the PML-RARa oncoprotein [J].BIood,2011,117(15):4095-4105.
  • 6Sanz MA, Grimwade D, Tallman MS, et al. Management of acutepromyelocytic leukemia:Recommendations from an expert panel onbehalf of the European Leukemia Net [J],Blood,2009,113 (9): 1875 -1891.
  • 7Higgins JPT,Grenn S.Cochrane Handbook for Systematic Reviews of Interventions Version 5.0.0.London:The Cochrane Collaboration,2008.
  • 8张奇.砷剂为主治疗急性早幼粒细胞白血病疗效分析与辨证分型探讨.中国中医科学院,2010.
  • 9苏秀连,夏维林.维甲酸联合砷剂治疗初发APL的临床疗效观察.基础医学论坛,2006,10(4):338-339.
  • 10黄子钦,杨建民,陈莉,倪雄,楼敬伟,王健民.三氧化二砷和全反式维甲酸治疗急性早幼粒细胞白血病疗效观察[J].齐齐哈尔医学院学报,2007,28(18):2177-2179. 被引量:5

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