他克莫司软膏治疗口腔扁平苔藓的临床分析

Clinical Study on Tacrolimus Ointment in Treatment of Oral Lichen Planus

目的：探究口腔扁平苔藓患者采用他克莫司软膏治疗的方法和效果。方法选取2013年3月～2014年9月收治的35例口腔扁平苔藓患者进行治疗，随机分组，实验组18例患者选择他克莫司软膏的治疗，对照组17例患者选择患者卤米松乳膏的使用，观察治疗后的改善情况。结果实验组治疗有效率为94.44%，对照组治疗有效率为82.35%，差异显著，且两组患者不良反应率也有较大差异（P均＜0.05）。

Objective To explore treatment method and its effect of Tacrolimus ointment in treatment of oral lichen planus. MethodsChoose 35 patients of oral lichen planus who are treated in hospital from March 2013 to September 2014 and separate them into two groups at random, 18 patients in study group are given Tacrolimus ointment treatment, while 17 patients in control group are given Halometasone ointment treatment, and then make a comparative study on patients’ recovery between two groups. ResultsPatients’ treatment efifcacy in study group is up to 94.44%, while patients’ treatment efifcacy in control group is up to 82.35%; there is a great differential between two groups in terms of treatment efifcacy as well as side-effect incidence and such a differential has statistic value（P〈0.05）. Conclusion Tacrolimus ointment is of efifcacy in treatment of oral lichen planus; it is conducive to relieving patients’ pain in short time without any side effect; and such a treatment method is quite safe and efifciency, therefore, it is worthwhile to be promoted widespread.